Current vacancies

Advanced Research Assistant

Salary range: £26,960 to £32,622 per annum depending on experience plus excellent benefits.

Fixed-term: 2- 3 years

A research assistant position is available for a talented advanced research assistant to join an interdisciplinary team of academic and drug discovery researchers. This is an exciting opportunity for the successful candidate to apply cutting-edge technology, including induced pluripotent stem cells (iPSC), intestinal organoids, CRISPR/Cas9 genome editing, cell ‘hashing’ and single cell RNA-sequencing, with the goal of validating genetic variants that are associated with predisposition to (IBD). The project forms part of a large programme of work led by Open Targets, which aims to identify novel therapeutic targets for inflammatory bowel disease (IBD). Open Targets is a public-private initiative between the Wellcome Sanger Institute (WSI), EMBL-EBI, GlaxoSmithKline, Biogen, Celgene, Takeda and Sanofi, to combine large-scale genomic experiments with statistical and computational methods to identify and validate the causal links between targets, pathways and diseases.

 The successful candidate will be based at the WSI within the laboratories of Dr. Carl Anderson (www.andersonlab.info) and will work closely on the project with Dr. Rebecca McIntyre (Senior Staff Scientist), with scientific input from Dr Gosia Trynka (Group Leader, WSI), Dr Matthias Zilbauer (University of Cambridge) and senior scientists based at GSK and Takeda. The post-holder will differentiate up to 50 lines of genetically engineered iPSC to intestinal organoids, and will stimulate them with cytokines to better mimic the inflammatory environment of the gut in IBD. Cells from primary intestinal organoids (cultured by the Zilbauer group) and iPSC-derived intestinal organoids will be prepared for single cell RNA-sequencing using ‘cell hashing’ and the 10X Genomics Chromium platform. We welcome candidates with experience in stem cell and/or organoid culture. The candidate will have the opportunity to interact with other research teams at the WSI and our industrial partners.

Reference:83373

Advanced Research Assistant - CASM

Salary in the region of £26,960 - £32,622 (dependent on experience) plus excellent benefits

Permanent / Open Contract

We are seeking an enthusiastic Advanced Research Assistant to carry out both routine and more bespoke laboratory protocols and procedures. They will work as part of the support team providing solutions for the Cancer, Ageing and Somatic Mutation Programme led by Peter Campbell and other members of faculty at the Sanger Institute. Supervisory responsibility for the day-to-day operation of the laboratory will be a key requirement of the role and it will be expected that the successful candidate will be able to use their skills and experience to trouble shoot and innovate where required. Excellent verbal and email communication is essential to keep both the team and senior staff fully appraised of progress.

Reference:83391

Advanced Research Assistant - Cellular Genetics

Salary in the region of £26,960 - £32,622 (dependent on experience) plus excellent benefits

Permanent / Open Contract

The Cellular Genetics Programme is seeking an enthusiastic individual to join their newly formed wet lab support team as an Advanced Research Assistant. 

You will carry out a range of research activities in a dynamic core team that supports the faculty research of the Programme. You will also interact with our Operations teams to submit samples for further analysis including sequencing.

You will have the opportunity to focus on a variety of protocols, including but not limited to; sample preparation, PCR, RNA/DNA purification, preparation of libraries for RNA sequencing and a variety of cell based assays. You will work within the support team to test and implement new protocols and scale them up as required by the faculty research groups, working towards delivering the protocols without requiring close supervision.

This is an excellent opportunity for a motivated and adaptable individual to support the cutting edge science delivered within the Cellular Genetics Programme.

This role may require occasional out-of-hours work according to the Institute’s overtime policy

Reference:83410

Assistant IT Manager-Advanced Courses and Scientific Conferences

Salary range: £28,000-£31,858 per annum depending on experience plus excellent benefits

Advanced Courses & Scientific Conferences is seeking an experienced and enthusiastic Assistant IT Manager to support our expanding programme of UK, overseas and online courses.

Part of Connecting Science at the Wellcome Genome Campus, we fund, develop and deliver over 60 training courses and conferences annually that span basic research, cutting-edge biomedicine and the application of genomics in healthcare.

Reporting to our IT Manager, you will support the set up and testing of computational teaching resources for each of our courses.

Liaising with the course instructors and other stakeholders, including on-site Systems Administration Teams, you will identify software and other computational requirements as well as set up Windows Virtual Machines for each course.

You will provide support during the course to ensure smooth running of the teaching sessions. You will also support the delivery and development of computational resources for our overseas courses in Africa, Asia and Latin America, as well as our new programme of online courses.

You will assist the IT Manager in the day-to-day maintenance and development of our IT training facilities and resources at the Genome Campus, including editing our WordPress website.

Working as part of a busy team, you will have the experience and confidence to work in a dynamic and fast-paced environment and deliver effective IT support across a busy programme.

During the courses you will need to work flexible hours (weekends and evenings). Overseas travel to support our courses in Africa, Asia and Latin America will also be an option after a suitable period of training and evaluation.

Reference:83400

Bioinformatics Apprentice - IT (4 years)

Salary in region of £17,489 per annum plus benefits

Apprentice FTC 4 Years 

We are looking for enthusiastic and passionate individuals to join our Computational Support team as an Apprentice whilst working towards gaining a BSc (Hons) Bioinformatics Degree Apprenticeship at Anglia Ruskin University.

You will have the opportunity to develop in the area of IT and Bioinformatics, gaining valuable skills whilst working towards making a contribution to the institute. You will be given the appropiate training and learn from our experienced team where you will go on to:

• Develop and maintain Bioinformatics services and support for those new services
• Assist our scientist in their use of HPC and Cloud technologies
• Assist in the production running of large-scale scientific compute and data management
• Interact with our on-site scientists and informaticians as they tackle tomorrows scientific challenges

About us: 

Our team is responsible for: large scale HPC, Cloud compute, Sangers large scale iRODS data repository and we provide and develop services and support for our bio-informatics teams. You will be involved in all key activities, with the intention to develop and take on more responsibilities as your knowledge and skills grow.

During your apprenticeship we can offer you:

• A mentor and membership to our mentoring program to explore your long-term opportunities
• A permanent publicly available portfolio of your coding and development 
• A comfortable working environment with a first name culture, informal dress code, and company social calendar 

Our Benefits: 

• 25 days annual leave, increasing by one day a year to a maximum of 30
• Family friendly environment including options for flexible and part-time working, a childcare voucher scheme, Campus Nursery and Summer holiday club
• Two days paid Employee Volunteering Leave a year
• Employee Discount Scheme
• Campus Gym, tennis courts, cricket pitch and sports hall plus a range of dining facilities
• Active Campus Sports and Social Club
• Free Campus Bus Service

Reference:83388

Bioinformatics Support Engineer - Pathogen Informatics

Salary in the region of £36,737 - £44,451 (dependent on experience) plus excellent benefits

Permanent/ Open Contract

We are looking to recruit an enthusiastic Bioinformatics Support Engineer for the Pathogen Informatics team, which provides informatics support to members of the Parasites and Microbes programme.

You will be an excellent communicator and problem solver with a strong interest in biological data, and passionate about providing a high level of customer service. You will work within a team of seven software developers and bioinformaticians, and will act as frontline support for requests from members of the programme. You will be responsible for monitoring the helpdesk and responding to submitted user issues, managing and performing software installations, ensuring smooth running of data through automated analysis pipelines, performing submissions and updates to public data repositories, and where appropriate assigning requests and bug reports to other members of the team.

The team is based on the principles of agile development and strongly promotes open source software development using GitHub for all software projects. This is an excellent opportunity for you to work in a dynamic software development and support team with opportunities to gain significant experience in areas such as genome sequencing, advanced UNIX, Python and bash scripting, software version control, software development practices, and bioinformatics analysis. Moreover, it is an exciting opportunity to support world-leading research groups in understanding infectious diseases such as malaria, tuberculosis, and pneumonia, and thus contribute to improving global health. 

Reference:83379

International Fellows Programme

The opportunity

We are seeking to appoint International Fellows to contribute to the Institute’s scientific portfolio.  Fellows should be early career stage scientists with existing faculty positions in a low or middle income country. Applications from senior scientists whose proposals are tightly aligned with the Institute’s strategic direction will also be considered.

The Institute is an internationally renowned genomic research centre with nearly 35 core faculty teams and 1,100 employees, based south of Cambridge. Our mission is to use genomic data to advance understanding of the biology of humans and pathogens in order to improve human health. With core funding and state-of-the-art platforms in sequencing, model organisms, cellular genetics and information technology, we enable our researchers to concentrate on biological questions across a diverse range of genomic and genetic science, in both independent studies and large-scale collaborations. The result is a unique, vibrant and interactive research environment with synergies and cross-fertilisation of ideas across and between our research programmes. 

We welcome applications from candidates whose research interests complement one of our four research programmes, wish to work closely with Sanger faculty and are able to bring in new capabilities and new ideas. Applications from individuals who have a different scientific focus within the broad field of genomics are also welcome. 

The successful candidates will initially be appointed for two years, with the potential for renewal for an additional two years upon successful review. Fellows will be allocated a yearly budget that can be used for research costs, as a stipend to supplement salary costs at their home institution, as well as travel costs.

To maximise the impact of our International Fellows programme, Fellows are expected to spend several months at the Wellcome Sanger Institute during their appointment, where they will benefit from access to the Institute’s fantastic research community and infrastructure. However, we understand this type of commitment could cause disruption to work and home-life and are very open to discussion surrounding flexibility with individual’s circumstances (please see below).

About you

Ideal candidates will have typically completed a PhD or MD within the past 10 years as well as having at least three years experience in a post-doctoral or clinical setting.  Candidates with more experience will need to demonstrate a well-defined research agenda that is relevant to the Wellcome Sanger Institute and impactful to their home Institution.  All candidates need to be associated with an institute of higher learning, research centre, or hospital within a low or middle income country.

About us

The Institute is located on the stunning Wellcome Genome Campus. This growing and dynamic site is the UK hub of genomic science. It hosts the European Bioinformatics Institute (EBI), Open Targets, a Biodata Innovation Centre, and Genomics England Limited’s 100,000 Genomes Sequencing Centre. The Campus is also home to the Wellcome Conference Centre and the Wellcome Genome Campus Connecting Science. Connecting Science inspires new thinking, sparks conversation and supports learning by drawing on the ground-breaking research taking place on the Campus.

What else do I need to know?

We have a dedicated Visa and Immigration adviser to provide expert, reliable advice on a range of immigration queries that support the global outlook and collaborative nature of the Institute. We are able to advise and support initial visa applications. Visa information will be discussed in more depth with successful applicants.

Reference:83421

Laboratory Manager - Cellular Genetics

Salary in the region of £34,305 - £41,508 (dependent on experience) plus excellent benefits

Permanent / Open Contract

The Cellular Genetics Programme is seeking an experienced laboratory manager to provide research support to multiple faculty teams across the programme; including but not limited to the groups led by Omer Bayraktar, Roser Vento and Sam Behjati. 

You would be involved in supporting the set-up and day-to-day running of the laboratories, to establish safe and productive working environments; working closely with the members of the Cellular genetics Wet Lab Support Team.

Duties would include:

• procurement and monitoring of consumables and reagents,
• acquisition and maintenance of laboratory equipment,
• ensuring all work carried out is compliant with health and safety regulations and research policies.

This is an excellent opportunity for a motivated and adaptable individual to support the cutting edge science delivered within the Cellular Genetics Programme.

Reference:83418

Learning and Development Coordinator

Salary range: £26,123 to £31,609 per annum plus benefits 

This is an exciting opportunity for a learning & development practioner to join our established Learning & Development team.  This role is vital in keeping the learning & development team functioning in the most efficient, professional and innovative way. The L&D Coordinator is the glue that holds the team together; offering sound advice, planning the core delivery and ensuring all training requirements are catered for.   You will implement effective administration processes in order to provide a smooth service.  This opportunity would suit an early careers Learning & Development practioner who is looking to develop wider experience of Learning & Development.

Reference:83404

Legal Counsel - (part time and flexi working considered)

Competitive salary plus benefits 

The Wellcome Sanger Institute is one of the premier centres of genomic discovery and understanding in the world. Through big, bold, exploratory research it continually seeks new ways to unlock, understand and harness the wealth of information stored within genomes, in order to improve health and life on earth.  As a result, it has been instrumental in some of the most significant initiatives and projects in genomics over the last 25 years. The Wellcome Sanger Institute leads ambitious collaborations across the globe to provide the foundations for further research and transformative healthcare innovations. Its success is founded on the expertise and knowledge of its people and the Institute seeks to share its discoveries and techniques with the next generation of genomics scientists and researchers worldwide.

We currently have two opportunities to join our small, one site based team reporting into the General Counsel. You'll have a minimum of 6 years PQE, but more experienced candidates are encouraged to apply. 

As Legal Counsel for Wellcome Sanger Institute, you’ll:

• Support our technology transfer team, research programmes and management operations teams, including advising them on a wide range of activities;
• Draft and negotiate a broad range of research, collaboration and similar agreements; and
• Work closely with our Faculty and Board of Management advising them on complex issues, implications, risks and courses of action.

Reference:83377

Postdoctoral Fellow (Computational) - Immunogenomics Group

Salary in the region of £31,897 - £39,240 (dependent on experience) plus excellent benefits

Fixed term for 3 years

We are looking for a computational biologist/statistical geneticist to join the Trynka group at the Wellcome Sanger Institute and advance our efforts in translating immune disease associated variants to function and improved treatment. Our group combines large scale experimental and computational work. We use immune assays to challenge cells in different conditions and measure cellular processes. The backbone to all our cellular readouts is a rich palette of genomic assays, which we use to profile gene expression regulation and chromatin activity. We also extensively use single cell RNA-seq technologies to generate large scale datasets to interpret gene expression regulation in immune cells at the single cell level.

We are seeking someone with strong research interests in genetics of autoimmune diseases, who is a team player, and will be actively involved in planning and leading the analysis of large-scale experiments. You should demonstrate strong statistical and computational skills, have past experience working with large scale genomic datasets. We are looking for someone creative, who will engage in the ongoing research projects as well as demonstrate independent thinking. You will contribute to the ongoing research projects and will be supported to formulate and develop your own scientific questions within the scope of the group’s interests.

We are an interdisciplinary group that includes immunologists, geneticists, molecular and computational biologists. Our group is a part of a dynamic and collaborative environment at the Wellcome Genome Campus. The position offers an exciting opportunity to work at one of the world-leading genomic research centres and to participate in the development and application of computational methods at the forefront of genomic research.

Reference:83392

Postdoctoral Fellow - Complex Disease Genetics

Salary range: £31,897-£39,986 per annum depending on experience plus excellent benefits.

Fixed Term Contract for 3 Years.

Applications are invited for a 3-year Postdoctoral Fellowship at the Wellcome Sanger Institute based jointly in the teams of Dr. Carl Anderson (Human Genetics Programme, www.andersonlab.info) and Dr. Maya Ghoussaini (Open Targets). This is an exciting opportunity for you to bring together cutting-edge genetic and genomic datasets to identify novel candidate therapeutic targets for inflammatory bowel disease (IBD). IBD is a chronic and debilitating disease of the gastrointestinal tract that affects 0.5% of the European population. The etiological basis is poorly understood and, as a result, existing therapeutics often fail, leaving patients to face life-changing surgical procedures. 

Genome-wide association studies have identified 240 regions of the human genome associated with IBD susceptibility. As for the majority of complex disease GWAS hits, the causal variants at the majority of these loci are unknown but are believed to have their effect on disease by changing the expression of nearby genes. In order to extract causal biological insights from IBD GWAS discoveries, and identify potentially novel therapeutic targets, a vital next step is to identify these genetically dysregulated genes and discover which other phenotypes these are associated with.

During this fellowship, you will lead a collaborative project to build a causal evidence base for every gene within IBD associated GWAS loci. Your affiliation with the Ghoussaini Team will bring access to the massive cross-disease genetic and genomic datasets aggregated by Open Targets and presented in their web-based portals (www.targetvalidation.org and https://genetics.opentargets.org). As a member of the Anderson group, you will also have access to the latest large-scale genetic association data for IBD.

Open Targets (www.opentargets.org/) is a public-private initiative between the EMBL-EBI, GlaxoSmithKline (GSK), Biogen, Celgene, Takeda, Sanofi and the Wellcome Sanger Institute (WSI). You will benefit from working closely with other scientists from Open Targets partner institutions with expertise in statistical genetics, inflammatory bowel disease and drug development. As such, this fellowship will suit a self-motivated individual with good communication skills who is looking to make a personal contribution to genomic research at the interface of academia and the pharmaceutical industry.

Reference:83355

Postdoctoral Fellow - Functional Genomics

Salary range: £31,897-£39,986 per annum depending on experience plus excellent benefits.

Fixed Term Contract for 3 Years.

Applications are invited for a 3-year Postdoctoral Fellowship within the Genomics of Inflammation and Immunity group at the Wellcome Sanger Institute (WSI), headed by Dr. Carl Anderson (www.andersonlab.info). Our group uses large-scale genetic and genomic data to understand the biological basis of inflammatory bowel disease (IBD) risk and progression. The ultimate goal of our IBD research is to identify new drug targets for the disease, and ascertain which individuals should be prescribed a given drug.

We have been awarded funding from the Crohn’s Colitis Foundation (CCF) to generate single-cell transcriptomic data from intestinal biopsies obtained from 160 IBD patients undergoing colonoscopy. All individuals will also be genotyped, with the goal of combining these datasets to map eQTLs across the more than forty different cell-types in the inflamed gut. The results from these analyses will then be combined with our detailed maps of IBD risk loci (and other gastrointestinal diseases) to identify genes that are dysregulated to bring about disease. The ultimate goal of the research is thus to improve our basic knowledge of IBD pathogenesis and identify novel candidate drug targets for treating disease.

You will use your established expertise in single-cell genomics and/or QTL mapping to lead the analysis and ensure that the project delivers on its ambitious goals. You will take intellectual ownership of the project and think broadly about questions that can be addressed using the data. You will collaborate closely with other members of the Anderson Lab working on a similar project to build a single-cell derived map of gut eQTLs from biopsies ascertained from 300 healthy individuals. As such, this project will suit a self-motivated individual with good communication skills who is looking to make a personal contribution to genomic research.

Reference:83352

Postdoctoral Fellow - Immunology / Infection Biology

Salary range: £31,897 to £39,986 depending on experience

Fixed term for 3 years

We are looking for a postdoctoral scientist interested in discovering novel mechanisms of immunoregulation by malaria-causing Plasmodium parasites. The Cell Surface Signalling Laboratory at the Wellcome Sanger Institute led by Dr Gavin Wright uses systematic protein-based approaches to identify extracellular receptor-ligand interactions that are important for infection with the ultimate aim of identifying new interventions and therapeutic targets.

The project will involve refining and implementing innovative biochemical and cellular methods to deepen our molecular understanding of how Plasmodium parasites interact with their mammalian hosts. The primary objective will be to identify novel host-pathogen receptor-ligand interactions using established high throughput technologies developed in the laboratory and to determine their functional role. We are particularly interested to hear from candidates with experience in basic immunological mechanisms who are interested in applying these at the interface of host-pathogen interactions.

For informal discussion, please contact Gavin Wright (gw2@sanger.ac.uk) 

Reference:83417

Postdoctoral Fellow - Machine Learning for antimicrobial resistance

Salary in the region of £31,897 - £39,240 (dependent on experience) plus excellent benefits

Fixed term for 2 years 

We are looking for a post-doctoral fellow for two years to work on the application of machine learning approaches to the detection and prediction of antimicrobial resistance determinants in clinical bacterial pathogens. Antimicrobial resistance is an increasing threat, and proper stewardship of our remaining antimicrobials, along with successful treatment of patients, will require rapid prediction of resistance as close to the patient bedside as possible.

The successful candidate will use machine learning tools on large datasets of sequenced and phenotyped clinical isolates to uncover molecular signatures of resistance that can be used to predict resistance from genome sequences, and inform the development of point-of-care tests. They will initially work on Staphylococcus aureus, Escherichia coli and Klebsiella, before broadening out to other pathogens. They will join the group of Julian Parkhill, working closely with the group of Sharon Peacock at the University of Cambridge, and with the startup company Next Gen Diagnostics, on the Wellcome Genome Campus.

Experience of the management and analysis of large genetic datasets using advanced bioinformatic and statistical techniques is essential, and familiarity with machine-leaning approaches will be a strong advantage.

For informal discussion, please contact Julian Parkhill (parkhill@sanger.ac.uk) 

Reference:83368

Postdoctoral Fellow - Single Cell Genomics

Salary range: £31,897-£39,986 per annum depending on experience plus excellent benefits.

Fixed Term Contract for 3 Years.

Applications are invited for a 3-year Postdoctoral Fellowship within the Genomics of Inflammation and Immunity group at the Wellcome Sanger Institute (WSI), headed by Dr. Carl Anderson (www.andersonlab.info). Our group uses large-scale genetic and genomic data to understand the biological basis of inflammatory bowel disease (IBD) risk and progression. The ultimate goal of our IBD research is to identify new drug targets for the disease, and ascertain which individuals should be prescribed a given drug.

The project will generate single-cell transcriptomic data from intestinal biopsies obtained from 300 healthy individuals undergoing colonoscopy. All individuals will also be genotyped, with the goal of combining these datasets to map eQTLs across the more than forty different cell-types in the gut. The results from these analyses will then be combined with our detailed maps of IBD risk loci (and other gastrointestinal diseases) to identify genes that are dysregulated to bring about disease. The ultimate goal of the research is thus to improve our basic knowledge of IBD pathogenesis and identify novel candidate drug targets for treating disease.

This project forms part of the Open Targets collaboration (www.opentargets.org/), a public-private initiative between the Wellcome Sanger Institute (WSI), EMBL-EBI, GlaxoSmithKline (GSK), Biogen, Celgene, Takeda and Sanofi to combine large-scale genomic experiments with statistical and computational methods to identify and validate the causal links between targets, pathways and diseases. As a postdoctoral fellow working on this project, you will also benefit from close interactions with collaborating scientists from Open Targets pharmaceutical partners.

Based at the WSI, you will use your established expertise in single-cell genomics and/or QTL mapping to lead the analysis and ensure that the project delivers on its ambitious goals. You will take intellectual ownership of the project and think broadly about questions that can be addressed using the data. You will collaborate closely with other members of the Anderson Lab working on a similar project to build a single-cell derived map of gut eQTLs from biopsies ascertained from Crohn’s disease patients with active inflammation. As such, this project will suit a self-motivated individual with good communication skills who is looking to make a personal contribution to genomic research at the interface of academia and the pharmaceutical industry.

Reference:83354

Postdoctoral Fellow - Statistical Genetics

Salary range: £31,897-£39,986 per annum depending on experience plus excellent benefits.

Fixed Term Contract for 3 Years.

Applications are invited for 3-year Postdoctoral Fellowships within the Genomics of Inflammation and Immunity group at the Wellcome Sanger Institute, headed by Dr. Carl Anderson www.andersonlab.info.

Our group uses large-scale genetic and genomic data to understand the biological basis of inflammatory bowel disease (IBD) risk and progression. The ultimate goal of our IBD research is to identify new drug targets for the disease, and ascertain which individuals should be prescribed a given drug.

Genome-wide association studies have identified hundreds of common loci associated with immune-mediated disease, though the causal variants at the majority of these loci remain unknown. Furthermore, the role of rare genetic variants in IBD is poorly defined, largely because powerful rare-variant association studies, likely requiring tens of thousands of sequenced cases and controls, are yet to be performed. By combining massive-scale genetic datasets with functional genomic data from a number of relevant primary cell types, the successful fellow will lead a research project that contributes to addressing one of three high-level questions:

a) What role does rare coding and non-coding genetic variation play in shaping IBD risk and progression?

b) What cell types and pathways are dysregulated in IBD, and how do genetic risk variants shape this dysregulation?

c) Can deep clinical, genetic and molecular data be used predict which drug should be prescribed to a given patient to bring about and maintain disease remission.

To achieve these ambitious research goals, Fellows will have access to a number of large-scale genetic datasets derived from well-phenotype cohorts of IBD patients, including GWAS data on around 80K cases, whole-exome sequence data on more than 40K IBD cases, and whole-genome sequence data (20X coverage) on 7K patients. The subset of these patients that have been recruited via the IBD bioresource (N~17K) (http://www.ibdbioresource.nihr.ac.uk/) are recallable by genotype and phenotype for downstream studies. Equivalently large cohorts of population controls are available for comparison. In addition to these genetic datasets, we are also generating single-cell transcriptomic profiles from intestinal biopsies ascertained from hundreds of IBD patients and controls, and undertaking eQTL mapping.

In addition to making use of these existing resources, Fellows are encouraged to propose specific research questions that require the creation of new genomic datasets, enabled by the group's extensive network of clinical and scientific collaborators, and Sanger's world-class core data-generation pipelines.

We are looking for individuals who enjoy scientific problem solving, are creative thinkers, have experience analysing large-scale genetic and genomic datasets, work effectively in a multi-disciplinary environment and are looking to establish a long-term career in scientific research. A strong publication record and an interest in the immune system and its diseases would be an advantage.

Reference:83357

Principal Technicians / Animal Technicians / Trainee Animal Technicians

Do you want to care for animals? 

Looking for a new opportunity?

We have part time, full time and flexible working opportunities for:

• Trainee Animal Technician; Salary range £17,489 to £20,832
• Animal Technician; Salary range £20,453 to £24,748
• Principal Animal Technician: Salary range £27,030 to £32,707

Additional pay through overtime, weekend and bank holiday working 

About us:

We have a state of the art animal facility providing a controlled environment for the mice, and fish housed within it using IVC technology.

Our state of the art facility provides

• a dedicated animal barrier,
• germ free and containment giving provision for the housing and utilisation of model organisms in research in breeding colonies and experimental groups. 

Daily task and responsibilities for trainee/animal technicians would include:

• providing food and water for the animals and organising special diets if needed
• carrying out regular observations and health checks
• making sure that animals are clean, comfortable and behaving as expected
• keeping up high levels of hygiene for each animal
• monitoring heating, lighting and humidity
• monitoring the weight and growth of animals
• maintaining high standards of cleanliness throughout the animal facility
• keeping accurate records and inputting data onto computer systems.

As part of the team you will be required to participate in weekend/public holiday rota (1 weekend in 3) to ensure we are staffed and maintained at all times. You will receive an enhanced over time rate during these periods of work. 

Training and beyond:

We will provide you with all the appropriate training for you to fulfil your role and offer you a career pathway so you can continue to progress and learn new skills with us! 

Once you have the experience and have completed the training required, you could also be involved in setting up scientific studies and breeding animals. You may also train and mentor other Animal Technicians and trainees.

As a Principal Animal Technician you can expect to lead and own all technical and operational work and to provide and supervise skilled assistance to a range of users and members of the Facility.

For full details on any of these positions please see job descriptions. 

What we can offer:

Our employees have access to a comprehensive range of benefits and facilities including:

• Defined Contribution Pension Scheme and Life Assurance
• Group Income Protection
• Private Health Insurance
• 25 days annual leave, increasing by one day a year to a maximum of 30
• Family friendly environment including options for flexible and part-time working, a childcare voucher scheme and Campus Nursery
• Two days paid Employee Volunteering Leave a year
• Employee Discount Scheme
• Campus Gym, tennis courts, cricket pitch and sports hall plus a range of dining facilities
• Active Campus Sports and Social Club
• Free Campus Bus Service

Reference:83394

Project Manager

Salary in the region of £45,886 - £56,083 (dependent on experience) plus excellent benefits

Permanent/ Open Contract

The Cellular Genetics Programme is looking for a talented and enthusiastic Project Manager to support the cell atlasing projects carried out across the Programme. The successful candidate will be an outstanding communicator with experience managing multiple projects. The ability to digest complex information and adapt plans accordingly will be key, coupled with a solid understanding of escalation processes and relevant regulations governing the research. 

You will work in a matrix environment interacting with stakeholders from within the Programme, the wider Institute, and with our global collaborators. Well-honed interpersonal skills and the ability to form and maintain strong working relationships with a diverse group of individuals is critical.

Practical experience of producing and managing budgets is essential, with demonstrable experience of delivering multiple overlapping projects within budget being highly advantageous. 

You will be responsible for understanding the different funding and sample sources that contribute to each overall project, and to track the progress of these projects against the various deliverables. In addition to the Sanger cell atlasing projects run out of several Faculty groups, you will work with the scientific leads to help map the outputs against the broader, global Human Cell Atlas project.

The ideal candidate will have a passion for supporting scientific research, and will be joining a growing team of individuals from a variety of disciplines all working together to deliver an exciting and cutting edge project.

Reference:83401

Research Assistant

Salary range £19,709 to £23,848 per annum plus benefits 

Full and part time applications will be considered (pt 25 hours per week/ft 37 hours per week) 

We are seeking a highly motivated and flexible individual to join our team. As a Research Assistant you will be working the laboratory where you will be responsible for performing either routine techniques in a high throughput environment or niche processes in a bespoke environment in line with SOP's.

The DNA Pipelines department (DNAP) has a central role within Wellcome Sanger Institute, delivering high quality data to our faculty and their collaborators over a range of techniques and platforms. These include, but are not limited to, Sequencing using Illumina & PacBio technologies, Genotyping using Illumina, Agena BioScience and Fluidigm technologies and BioNano Genome mapping. We have a Sample Logistics team providing import and export of samples globally and internally. This team also offers extraction services utilising Qiagen technologies.

You will be working as part of a team and you'll produce quality data within defined time frames and assist with the everyday running of the laboratory.

We will consider applications from recent graduates in a scientific discipline looking to start a career in molecular biology and gain experience in a range of techniques.

Reference:83397