Advanced Job Search Results

Advanced Job Search Results

Advanced Job Search Results

Here you can take a quick look at the current jobs on offer. There are three ways of doing this: you can select on date posted, select criteria for the type of job you are interested in using the checkboxes and/or the free text.

Advanced Research Assistant (Flow Cytometry)

We have a new opportunity for an Advanced Research Assistant to join us in our state-of the art Cytometry Core facility (CCF) We are a busy high end multi-user unit servicing internal researchers and external collaborators.

About the role:

You will be working as part of an established team of flow cytometry specialists providing flow cytometric cell analysis as well as cell sorting service to our researchers.

You will be responsible for the day-to-day operation and maintenance of flow cytometers. You will train and support other members of staff/researchers in the use of the equipment.

You will also be expected to provide technical support for the facility, carrying out essential quality control procedures, instrument maintenance and troubleshooting.

This is an excellent opportunity for anyone who is interested in specialising in an exciting and rapidly developing field.

About the team:

The flow cytometry facility is a dedicated scientific service offering investigators with state of art flow cytometry instrumentation together with assistance in running samples, data analysis and experimental design.

The facility supports a wide range of flow cytometric techniques including analysis and isolation of chromosomes (flow karyotyping), cellular phenotyping, single cell sorting for transcriptomic assay, CRISPR-Cas9 knockout bulk cell sorting for genome wide screening etc.  Currently, the facility is equipped with 9 flow cytometers. These include high throughput cell analysers (BD LSRll, BD LSRFortessa, Beckman Coulter Cytoflex) and high speed cell sorters (Mo-Flo Legacy, Mo-Flo XDP, BD INFLUX and Sony MA900).

Grade: 3 Salary per annum: 26,960 to 32,622 - dependent on experience Full Time or Part Time: Full Time Contract Type: Permanent Reference:83621

Advanced Research Assistant - Cellular Genetics

An exciting opportunity has arisen for an Advanced Research Assistant to support the research of the Cellular Genetics Programme, as a member of the core wet lab support team. You will join a dynamic team and work collaboratively across the Programme, the Sanger Institute and the wider scientific community to support a wide variety of projects including the Human Cell Atlas work being undertaken in Cellular Genetics.

You will play a fundamental role within the team which provides expertise to support; the development and implementation of pioneering spatial genomic technologies including spatial transcriptomics and RNAscope and also bespoke sequencing library creation for gene expression, immune cell profiling and chromatin accessibility analysis of single cells or nuclei in preparation for downstream NGS analysis.

You will work to test and implement new protocols and scale them up as required by the faculty research groups, working towards delivering the protocols without requiring close supervision. You will interact with external collaborators to support sample acquisition logistics, sample management and processing and also with our operations teams to submit samples for further analysis.

Excellent communication and relationship-building skills alongside strong time management and organisational skills are needed as is the ability to troubleshoot and identify areas for process improvement.

This is an excellent opportunity for a motivated and adaptable individual to support the cutting edge science delivered within the Cellular Genetics Programme.

Grade: 3 Salary per annum: 26,960 to 32,622 Full Time or Part Time: Full Time Contract Type: Permanent Reference:83641

Advanced Research Assistant - Open Targets

We are looking for a highly motivated Advanced Research Assistant to join a collaborative, large-scale project that aims to understand the cellular basis of neurodevelopmental disorders. The prospective candidate will be involved in studying how mutations in chromatin modifying enzymes affect neuronal development and cause disease. The primary goal of the work is to culture and differentiate human iPS cells with and without mutations to neuronal cell types, and profile the cells with a range of cellular and genomic assays. This is an exciting opportunity to be engaged in all aspects of a cutting-edge research project, from planning and pilot work to data generation and novel discoveries.

The project forms part of the Open Targets collaboration ( and provides a unique opportunity to deliver translational science together with industry partners including GSK, Celgene, Sanofi, and Takeda. The prospective candidate will work at the Wellcome Sanger Institute with Dr. Helena Kilpinen and the Cellular Generation and Phenotyping (CGaP) core facility, collaborating closely with the Hurles group and other members of the Open Targets team.

Grade: 3 Salary per annum: 26,960 to 32,622 Full Time or Part Time: Full Time Contract Type: Fixed Term Contract Length: 2 years with the possibility of extension Reference:83615

Advanced Research Assistant -Gene Editing Team

We are seeking to recruit multiple enthusiastic, well organised and technically minded Advanced Research Assistants to perform a wide variety of genome engineering projects and develop gene modification techniques using CRISPR/Cas9 technology. You will work as part of the newly formed Gene Editing team within the Cellular Operations division, led by Dr Oliver Dovey.

  • Permanent and Fixed term opportunities available
  • Secondment opportunities available for internal candidates. Manager approval will be required in advance. 

About us:

The Gene Editing Team supports the gene editing needs of the Institute’s varied research programmes, through the adoption of modern genome editing techniques. Optimising and developing genome editing tools and platforms we provide an agile, project-focused service for our collaborating partners. You will have the opportunity to contribute to our expanding portfolio of projects which includes but is not limited to; high throughput generation of targeting vectors, generation of bespoke mutant or tagged human-iPSCs, gene targeting in primary cells and cell lines, manufacture of arrayed/pooled guide RNA libraries, single cell gene editing applications and Cas mediated gene regulation.

The Gene Editing Team is a part of a dynamic and collaborative environment at the Wellcome Genome Campus. This is an exciting opportunity to work at one of the world-leading genomic research centres and to participate in the development and application of modern gene editing techniques at the forefront of current genomic research.

Grade: 3 Salary per annum: 26,960 to 32,622 Full Time or Part Time: Full Time Contract Type: Permanent Contract Length: 3 perm and 1 12 month FTC maternity cover Reference:83623

Research Assistant - DNA Pipelines

Salary range £19,709 to £23,848 per annum plus benefits 

Full and part time applications will be considered (pt 25 hours per week/ft 37 hours per week) 

We are seeking a highly motivated and flexible individual to join our high throughput team in DNA pipelines.

As a Research Assistant you will be working exclusively in the laboratory utilising our cutting edge automation in order to process samples. The environment operates in a high throughput capacity, of which diligence and the adherence to standard operating procedures is paramount in order to maintain the quality of data being produced.

You will be working for the DNA Pipelines department which has a central role within the Institute, delivering data to our faculty and external collaborators over a range of techniques and platforms. DNA library construction is carried out using various liquid handlers such as: TTP Labtech mosquito, Agilent Bravo, Hamilton and Beckman robotics. The libraries are then sequenced on Illumina Sequencing instruments: MiSeq, HiSeq 2500, HiSeq 4000, HiSeq X and NovaSeq.

Furthermore, you will be working predominantly as part of a team producing data within defined time frames. You will also assist with the everyday running of the laboratory which includes waste management, keeping the environment clean and organised whilst ensuring all equipment and tools are in good working order.

Applications from recent graduates in a scientific discipline looking to start a career in molecular biology and gain experience in a range of techniques to be considered.

Grade: 4 Salary per annum: 19,709 to 23,848 Full Time or Part Time: Full Time Contract Type: Permanent Reference:83622