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Research Assistant Cellular Generation and Phenotyping

Salary range: £18,422 to £23,027 dependent on experience

An exciting opportunity for two Research Assistants has arisen!

Two new positions have opened up, one permanent and one fixed term until 31 May 2018.

Deadline for applications is 11th December 2016.

The Cellular Generation and Phenotyping Core Facility (CGaP) is responsible for developing and delivering complex and large scale cell biology projects to support the breadth of scientific programs at the Sanger Institute.   The current portfolio of projects includes the generation of human induced pluripotent stem cells (iPSCs) and organoid lines, the differentiation and characterisation of the iPSC lines and the running of large scale CRISPR screens in cancer cell lines. Upcoming projects include differentiation of iPSCs into macrophages and challenge with stimuli, differentiation of iPSCs into neuronal precursors and cortical neurons and generation of P. falciparum mutants for a malaria project.

We are seeking 2 self-motivated, proactive individuals, interested in kick starting their career and breaking into the cell biology field. The successful individuals will be key members of the department, helping to deliver multiple cell biology projects.  The successful candidates will be involved in our CRISPR screening project and a macrophage differentiation project.   Once trained, the Research Assistants will be required to work both individually and as part of a project team to ensure targets are met. They must have good time management skills to enable them to cope with regularly changing priorities and workloads. They will also hold other responsibilities which will aid in the development and running of the department.

Job Reference

Essential Skills

  • A relevant BSc in a life science subject, or equivalent laboratory experience
  • Mammalian cell culture experience,
  • Good communication and willingness to present at team meetings,
  • Good organisational skills.
  • Team orientated approach

Ideal Skills

  • Experience of working with primary or stem cell lines
  • Experience/knowledge of CRISPR/CAS9 gene editing technology
  • Prior experience of cell based assays or antibody based staining techniques, such as immunofluorescence

Other information

The Sanger Institute is a charitably funded research centre focused on understanding the role of genetics in health and disease. We use state of the art large-scale genomic approaches to drive world-leading projects to uncover the basis of genetic and infectious disease. Our goal is to provide results that can be translated into diagnostics, treatments or therapies that reduce global health burdens.

The Institute is located near Cambridge, UK on the stunning Wellcome Genome Campus. This growing and dynamic site is the British hub of genomic science. It hosts the European Bioinformatics Institute (EBI), Open Targets, a Biodata Innovation Centre and will soon host Genomics England Limited’s 100,000 Genomes Sequencing Centre. The Campus is also home to the Wellcome Genome Campus Courses, Conferences and Public Engagement (CCPE) programme. The CCPE programme delivers training and engagement focused around genomics, its applications, and implications.  Its vision is to inspire a range of audiences both on the Campus and beyond it, and make the world of genomics open and accessible to all.

To help researchers to develop their skills and networks, the Institute hosts a range of scientific seminars with internal and invited speakers, scientific group meetings and skills development workshops. In addition the Campus is home to the Wellcome Trust Advanced Course and Scientific Conferences programme and the Wellcome Trust Conference Centre.

Our Benefits include: Defined Contribution Pension Scheme, Group Income Protection, Healthcare scheme, Childcare Vouchers, Workplace Nursery and 25 days Annual Leave, increasing by one day per year up to a maximum of 30, plus Bank Holidays. We also have a gym, two cafes, dining facilities, and a free campus bus service. Our thriving Sports and Social Club provides many opportunities to meet with people working across the campus.

Wellcome Trust Sanger Institute welcomes applications from all candidates irrespective of age, disability, gender, gender identity, sexual orientation, race, religion or belief, or marital or civil partnership status.

Please include a covering letter and CV with your application. 

Closing date: 11th December 2016