Postdoctoral Fellow - Malaria Genetics
Salary £31,115 to £39,004 plus excellent benefits.
Two years fixed term.
In the Sanger Institute Malaria Programme, we are generating large scale genomic and transcriptomic data and we are looking for driven individuals to join our analysis team. Our new initiative will generate thousands of parasite and mosquito genomes each year from around the globe. To make the most of these data, we want to implement additional technological (e.g., long read sequencing, single cell sequencing) and analytical (e.g., machine learning, variation graphs) advances. We are looking for postdocs with considerable expertise in these and/or other relevant areas who would drive these projects. Creativity and initiative are essential; the successful applicant will demonstrate dedication to leading this work while being part of a very large and multidisciplinary team, all of whom are invested in the projects.
The genetic observatories of parasites and vectors that we are developing build on our work with MalariaGEN partners in over 40 countries, e.g. through the open access Pf3k and Ag1000G projects. The new initiative will be a global partnership that proposes to increase by orders of magnitude the scale and resolution of data on the population genomics of the malaria parasite and mosquito vector. These data will be used to address fundamental scientific problems in host-parasite-vector interactions and evolutionary biology as well as practical applications in disease control, e.g. working with public health agencies to prevent the spread of drug and insecticide resistance.
Exceptional analytical skills are required as is a strong interest in genome biology. We are multi-disciplinary teams, and the successful applicant will work collaboratively with a range of other specialists in the Programme including wet lab scientists, data analysts and statisticians, and malaria and vector biologists and geneticists, so teamwork and a collaborative ethos are required. The applicant will be jointly supervised by Dominic Kwiatkowski and Mara Lawniczak.
- PhD in statistics, bioinformatics, population genetics or other relevant area of quantitative analysis
- Experience of processing extremely large datasets on parallel computing clusters
- Knowledge of bioinformatic methods for processing next-generation sequencing data or similar
- Strong analytical and problem solving
- Strong written and oral communication
- Strong skills in computer programming for advanced statistical analysis and large-scale data management
The Sanger Institute is a charitably funded research centre focused on understanding the role of genetics in health and disease. We use state of the art large-scale genomic approaches to drive world-leading projects to uncover the basis of genetic and infectious disease. Our goal is to provide results that can be translated into diagnostics, treatments or therapies that reduce global health burdens.
The Institute is located near Cambridge, UK on the stunning Wellcome Genome Campus. This growing and dynamic site is the British hub of genomic science. It hosts the European Bioinformatics Institute (EBI), Open Targets, a Biodata Innovation Centre and will soon host Genomics England Limited’s 100,000 Genomes Sequencing Centre. The Campus is also home to Wellcome Genome Campus Connecting Science. Connecting Science inspires new thinking, sparks conversation and supports learning by drawing on the ground-breaking research taking place on the Campus. Its mission is to enable everyone to explore genomic science and its impact on research, health and society.
To help researchers to develop their skills and networks, the Institute hosts a range of scientific seminars with internal and invited speakers, scientific group meetings and skills development workshops.
Our Benefits include: Defined Contribution Pension Scheme, Group Income Protection, Healthcare scheme, Childcare Vouchers, Workplace Nursery and 25 days Annual Leave, increasing by one day per year up to a maximum of 30, plus Bank Holidays. We also have a gym, two cafes, dining facilities, and a free campus bus service. Our thriving Sports and Social Club provides many opportunities to meet with people working across the campus.
Wellcome Trust Sanger Institute welcomes applications from all candidates irrespective of age, disability, gender, gender identity, sexual orientation, race, religion or belief, or marital or civil partnership status.
Please include a covering letter and CV with your application.
Closing date for applications: 5th April 2017, however applications will be considered and reviewed on an on-going basis and therefore the post may be filled before the deadline.