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Software Developer - Sequencing Informatics

An excellent opportunity to cultivate a rewarding career as a software developer

Salary range: £24,589 to £30,995 plus excellent benefits

Whether you are at the start of your career or established and looking for a new challenge, an exciting opportunity has become available for a software developer to join the New Pipelines Group (NPG). 

The NPG group is part of core sequencing informatics team at Wellcome Trust Sanger Institute.  We develop and maintain software for analysis and archival of sequencing and genotyping data produced by the high throughput facilities.

Members of the team work in close collaboration and opportunities for professional growth are encouraged through formal and informal training. You will have exposure to all elements of the software development cycle and work on diverse software projects. Most of the code developed by the team is available on GitHub:

The successful candidate will support and develop institute’s high throughput sequencing analysis and QC pipelines and tracking systems. In addition the candidate will work on a range of exciting projects, such as (1) making our computational pipelines cloud-ready, (2) highly efficient and scalable data streaming server and client applications, (3) analysis and QC pipelines, (4) applications for tracking sequencing instruments, (5) data archival, warehousing and visualisation.

This role is designed for graduates, those who are about to achieve their degree and for IT professionals or scientists with some software development experience. Bioinformatics experience is beneficial but by no means necessary. The candidate must have strong desire to work as a software developer and acquire cutting edge technical skills.

We welcome applications equally from those who wish to work full time (37 hours) or for a minimum of 30 hours per week via a flexible working arrangement.

Job Reference

Essential Skills

  • An undergraduate or postgraduate degree in Computer Science (or similar) or other science discipline
  • Some experience in one of the following: Python (virtualenv, pip), Node.js (streaming, Express, async, Promise), Perl (Moose, DBix::Class, CPAN).
  • An interest in using virtualization (VMs and/or Linux containers)
  • Use of version control software (Git)
  • Good written and verbal communication skills
  • Readiness to do self-directed learning
  • Attention to detail
  • Ability to work both on their own and as a part of a team

Ideal Skills

  • Experience of working with databases (using joins in relational databases, ORMs)
  • An interest in using Linux OS and shell scripting (looping, conditions, error capture)
  • Test automation and continuous integration
  • Web development and client side Javascript
  • Experience of working with large datasets (e.g. tens of thousands of 50 gigabyte files)
  • HPC under a job scheduler (LSF or OpenLava) or more contemporary pipeline solutions e.g. Apache Spark
  • NoSQL databases (e.g. CouchDB, MongoDB)

Other information

The Sanger Institute is a charitably funded research centre focused on understanding the role of genetics in health and disease. We use state of the art large-scale genomic approaches to drive world-leading projects to uncover the basis of genetic and infectious disease. Our goal is to provide results that can be translated into diagnostics, treatments or therapies that reduce global health burdens.

The Institute is located near Cambridge, UK on the stunning Wellcome Genome Campus. This growing and dynamic site is the British hub of genomic science. It hosts the European Bioinformatics Institute (EBI), Open Targets, a Biodata Innovation Centre and will soon host Genomics England Limited’s 100,000 Genomes Sequencing Centre. The Campus is also home to Wellcome Genome Campus Connecting Science. Connecting Science inspires new thinking, sparks conversation and supports learning by drawing on the ground-breaking research taking place on the Campus. Its mission is to enable everyone to explore genomic science and its impact on research, health and society.

To help researchers to develop their skills and networks, the Institute hosts a range of scientific seminars with internal and invited speakers, scientific group meetings and skills development workshops.

Our Benefits include: Defined Contribution Pension Scheme, Group Income Protection, Healthcare scheme, Childcare Vouchers, Workplace Nursery and 25 days Annual Leave, increasing by one day per year up to a maximum of 30, plus Bank Holidays. We also have a gym, two cafes, dining facilities, and a free campus bus service. Our thriving Sports and Social Club provides many opportunities to meet with people working across the campus.

Wellcome Trust Sanger Institute welcomes applications from all candidates irrespective of age, disability, gender, gender identity, sexual orientation, race, religion or belief, or marital or civil partnership status.

Please include a covering letter and CV with your application. 

Closing date: 15th June and applications will be considered on an on-going basis.