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Computational Genomics - Senior Staff Scientist

Salary range from: £38989 to £49602 plus excellent benefits.

A position is available for a Senior Staff Scientist in the Cellular Genetics programme at the Wellcome Trust Sanger Institute. The successful applicant will be responsible for the creation of a computational support team of 1-4 people to serve the needs of the Cellular Genetics faculty research groups. This is an exciting opportunity to oversee the creation of a team of excellent bioinformaticians that will handle very large functional genomics data sets being created by the Cellular Genetics faculty research teams. The post-holder will develop and implement highly efficient, robust computational workflows to handle a wide range of genomics data sets, including RNA-seq, ChIP-seq, ATAC-seq data from both bulk and single cell technologies. The position will involve line management of a team of skilled bioinformaticians, and regular communication and scientific interaction with members of the Cellular Genetics programme.

Candidates in Biology with a PhD in computational genomics or related fields are strongly encouraged to apply. We also welcome candidates with a PhD in Physics, Statistics or Computer Science with strong interests and background in computational biology and functional genomics. Excellent programming skills, experience with very large data sets in a high performance computing environment and an ability to work as part of a team are essential. Familiarity with cloud computing and Common Workflow Language would be desirable.

Job Reference

Essential Skills

  • A PhD in a computational area (computer science, computational genomics, statistical genetics)
  • Extensive knowledge of state of the art methods for functional genomics data, excellent knowledge of the relevant scientific literature
  • Excellent communication (verbal and written) and interpersonal skills
  • Experience with high performance computing and parallel processing in a *nix environment
  • Experience of line management, and ability to work well in a team
  • Excellent programming skills in both compiled and interpreted languages

Ideal Skills

  • Excellent data visualization skills
  • Experience with a wide range of genomics technologies (NGS, arrays, single cell tech)
  • Experience implementing computational workflows

Other information

The Sanger Institute is a charitably funded research centre focused on understanding the role of genetics in health and disease. We use state of the art large-scale genomic approaches to drive world-leading projects to uncover the basis of genetic and infectious disease. Our goal is to provide results that can be translated into diagnostics, treatments or therapies that reduce global health burdens.

The Institute is located near Cambridge, UK on the stunning Wellcome Genome Campus. This growing and dynamic site is the British hub of genomic science. It hosts the European Bioinformatics Institute (EBI), Open Targets, a Biodata Innovation Centre and will soon host Genomics England Limited’s 100,000 Genomes Sequencing Centre. The Campus is also home to Wellcome Genome Campus Connecting Science. Connecting Science inspires new thinking, sparks conversation and supports learning by drawing on the ground-breaking research taking place on the Campus. Its mission is to enable everyone to explore genomic science and its impact on research, health and society.

To help researchers to develop their skills and networks, the Institute hosts a range of scientific seminars with internal and invited speakers, scientific group meetings and skills development workshops.

Our Benefits include: Defined Contribution Pension Scheme, Group Income Protection, Healthcare scheme, Childcare Vouchers, Workplace Nursery and 25 days Annual Leave, increasing by one day per year up to a maximum of 30 days, plus Bank Holidays. We also have a gym, two cafes, dining facilities, and a free campus bus service. Our thriving Sports and Social Club provides many opportunities to meet with people working across the campus.

Wellcome Trust Sanger Institute welcomes applications from all candidates irrespective of age, disability, gender, gender identity, sexual orientation, race, religion or belief, or marital or civil partnership status.

Please include a covering letter and CV with your application.  

Closing date for applications: 29th August 2017, however applications will be considered and reviewed on an on-going basis and therefore the post may be filled before the deadline.