Salary Range: £31,115 to £39,004, plus excellent benefits.
Fixed term for 2 years.
We are looking for a postdoc interested in using single cell sequencing technologies to investigate malaria parasites, mosquito vectors, and vector/parasite interactions.
Malaria parasites are single celled organisms, and single cell technologies are revealing new levels of complexity in lab strains (see our preprint). At the Sanger Institute, we are now working towards a “Malaria Cell Atlas” that includes single cell RNAseq data from human malaria parasites across their lifecycle and mosquito tissues relevant for malaria transmission. This will serve as a reference database to then use single cell RNA sequencing approaches to understand parasite and vector biology more deeply in the context of natural infections. We will be working together with multiple colleagues from Africa in these efforts and there will be opportunities to spend time in endemic countries working with our collaborators.
Given the wide span of projects, we are particularly interested in hearing from applicants who have expertise in any of the following areas: working with malaria parasites or mosquitoes in the lab or in the field, parasite or dipteran genomics, and/or computational analysis of single cell or transcriptomic data from any organism. Creativity and initiative are essential and the successful applicant will demonstrate dedication to leading this working collaboratively with a range of other scientists. We value diversity and we welcome applications from anyone regardless of their gender, age, race, sexual orientation, religion, disability, nationality, or their requirement for part time or flexible working hours due to childcare or other commitments.
- PhD in molecular biology, statistics, bioinformatics, genomics, population genetics or other relevant area of molecular or quantitative analysis (E)
- Demonstrated analytical and problem solving skills (E)
- Clear written and oral communication skills (E)
- Knowledge and experience in a relevant field as evidenced by publication record (E)
- Ability to lead an area of work while working collaboratively (E)
- Ability to deliver high-quality scientific outputs from complex projects involving multiple partners (E)
- Experience of processing large datasets on parallel computing clusters (D)
- Experience of working with malaria parasites and/or mosquitoes (D)
- Knowledge of bioinformatic methods for processing next-generation sequencing data, transcriptomic data, or similar (D)
The Sanger Institute is a charitably funded research centre focused on understanding the role of genetics in health and disease. We use state of the art large-scale genomic approaches to drive world-leading projects to uncover the basis of genetic and infectious disease. Our goal is to provide results that can be translated into diagnostics, treatments or therapies that reduce global health burdens.
The Institute is located near Cambridge, UK on the stunning Wellcome Genome Campus. This growing and dynamic site is the British hub of genomic science. It hosts the European Bioinformatics Institute (EBI), Open Targets, a Biodata Innovation Centre and will soon host Genomics England Limited’s 100,000 Genomes Sequencing Centre. The Campus is also home to Wellcome Genome Campus Connecting Science. Connecting Science inspires new thinking, sparks conversation and supports learning by drawing on the ground-breaking research taking place on the Campus. Its mission is to enable everyone to explore genomic science and its impact on research, health and society.
To help researchers to develop their skills and networks, the Institute hosts a range of scientific seminars with internal and invited speakers, scientific group meetings and skills development workshops.
Our Benefits include: Defined Contribution Pension Scheme, Group Income Protection, Healthcare scheme, Childcare Vouchers, Workplace Nursery and 25 days Annual Leave, increasing by one day per year up to a maximum of 30, plus Bank Holidays. We also have a gym, two cafes, dining facilities, and a free campus bus service. Our thriving Sports and Social Club provides many opportunities to meet with people working across the campus.
Wellcome Trust Sanger Institute welcomes applications from all candidates irrespective of age, disability, gender, gender identity, sexual orientation, race, religion or belief, or marital or civil partnership status.
Please include a covering letter and CV with your application.
Closing date for applications: 12th October 2017, however applications will be considered and reviewed on an on-going basis and therefore the post may be filled before the deadline.