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Principal Software Developer - Pathogen Informatics

Salary in the region of £47,222 to £57,138 per annum plus benefits

We are seeking to recruit an experienced Principal Software Developer to work within the Pathogen Informatics team at the Wellcome Trust Sanger Institute.

The Pathogen Informatics team develop and maintain software applications and systems to support the research activities of the Infection Genomics programme. The Infection Genomics programme conducts large-scale experiments to investigate the underpinning mechanisms of evolution, infection and resistance to therapy in viruses, bacteria and parasites. The programme also focuses on the genetics of host response to infection and the role of the microbiota in health and disease. 

The Pathogen Informatics team play a key role in the the delivery of many of these large-scale pathogen projects. The successful candidate will be responsible for developing software and systems to manage, analyse, query and visualise the vast amounts of data produced by these projects, including next-generation sequence data and annotation and curation data.

The team is based on the principles of agile development so that the software can be rapidly prototyped, updated regularly and receive rapid feedback from scientists in the Infection Genomics program. The team employ a test-driven development strategy for all software development projects and strongly promote open source development using Github for all software projects.

This role would suit somebody with previous experience in the specification, design and delivery process of a software system (preferably in genomics or similar areas). The postholder will be expected to discuss and provide input for strategic decisions of the team, represent the team at internal and external meetings, and provide technical supervision to junior members of the team. Previous experience of next-generation sequencing informatics would be advantageous, although not strictly required.

Job Reference

Essential Skills

  • A degree in a scientific or engineering discipline (or equivalent industrial experience)
  • Significant programming experience in at least two programming languages
  • ・vidence of successful delivery in large or complex software projects and acting as a technical lead in both design and development
  • Experience of object oriented development
  • Knowledge and experience of UNIX/LINUX on an advanced level
  • Practical experience with running software on a compute farm
  • Knowledge of relational database systems and manipulation via SQL
  • Experience of managing large volumes of data
  • An ability to learn quickly on the job with excellent problem solving and analytical skill
  • Must be self-motivated and proactive with ability to manage own workload effectively
  • Strong interpersonal and communication skills

Ideal Skills

  • Experience and knowledge of genome annotation and curation
  • Previous experience in modern Perl (Moose)
  •  ̄revious people management experience
  • ・xperience with new sequencing technology data
  • 、n interest in web technologies with knowledge of HTML5 and JavaScript
  • ・xperience with agile software development methods
  • ・xperience of test driven development

Other information

The Sanger Institute is a charitably funded research centre focused on understanding the role of genetics in health and disease. We use state of the art large-scale genomic approaches to drive world-leading projects to uncover the basis of genetic and infectious disease. Our goal is to provide results that can be translated into diagnostics, treatments or therapies that reduce global health burdens.

The Institute is located near Cambridge, UK on the stunning Wellcome Genome Campus. This growing and dynamic site is the British hub of genomic science. It hosts the European Bioinformatics Institute (EBI), Open Targets, a Biodata Innovation Centre and will soon host Genomics England Limited’s 100,000 Genomes Sequencing Centre. The Campus is also home to Wellcome Genome Campus Connecting Science. Connecting Science inspires new thinking, sparks conversation and supports learning by drawing on the ground-breaking research taking place on the Campus. Its mission is to enable everyone to explore genomic science and its impact on research, health and society.

To help researchers to develop their skills and networks, the Institute hosts a range of scientific seminars with internal and invited speakers, scientific group meetings and skills development workshops.

Our Benefits include: Defined Contribution Pension Scheme, Group Income Protection, Healthcare scheme, Childcare Vouchers, Workplace Nursery and 25 days Annual Leave, increasing by one day per year up to a maximum of 30, plus Bank Holidays. We also have a gym, two cafes, dining facilities, and a free campus bus service. Our thriving Sports and Social Club provides many opportunities to meet with people working across the campus.

Wellcome Trust Sanger Institute welcomes applications from all candidates irrespective of age, disability, gender, gender identity, sexual orientation, race, religion or belief, or marital or civil partnership status.

Please include a covering letter and CV with your application.

Closing date:  31st January 2018