Salary in the region of £35,924 - £43,468 (dependant on experience) plus excellent benefits
Fixed Term Contract - 6 months
We are looking for a motivated individual to join the Bradley group at the Wellcome Sanger Institute.
This temporary position in the Bradley laboratory is funded by an award to support the translation of a project form the laboratory into a potential spin-out. The specific goals would be to demonstrate that the engineered mice could mount an effective immune response against one or more antigens and that isolated antibodies have features which make them suitable as potential therapeutics.
Applicants should have a background in ES cell manipulation, labelling cells for FACS, knowledge of the process of therapeutic antibody generation and the development of monoclonal antibodies as therapeutic drugs. We are seeking a creative, highly-motivated and productive individual.
- Project management experience
- Excellent organisational skills
- Tissue culture experience
- Experienced in ES cell manipulation, including targeted knock-Ins
- Hands-on, lab-based experience and in depth understanding of molecular biology techniques with focus on innovative approaches
- Hands-on lab based experience labelling cells for FACS
- People management experience
- Works well within in a team
- PhD in stem cells, cellular phenotyping and animal model (or equivalent)
- Ability to follow instructions accurately, efficiently & to work without supervision
- Good troubleshooting ability
- Attention to detail
- Strong communication skills
- Relevant PhD with post-doctoral experience
- Ability to interpret and respond to biological data sets
- Experience with protein expression
- Willingness to learn the process of therapeutic antibody generation and the development of monoclonal antibodies as therapeutic drugs
- Willingness to develop single cell methods for antibody discovery
The Sanger Institute is a charitably funded research centre focused on understanding the role of genetics in health and disease. We use state of the art large-scale genomic approaches to drive world-leading projects to uncover the basis of genetic and infectious disease. Our goal is to provide results that can be translated into diagnostics, treatments or therapies that reduce global health burdens.
The Institute is located near Cambridge, UK on the stunning Wellcome Genome Campus. This growing and dynamic site is the British hub of genomic science. It hosts the European Bioinformatics Institute (EBI), Open Targets, a Biodata Innovation Centre and the Genomics England Limited’s 100,000 Genomes Sequencing Centre. The Campus is also home to Wellcome Genome Campus Connecting Science. Connecting Science inspires new thinking, sparks conversation and supports learning by drawing on the ground-breaking research taking place on the Campus. Its mission is to enable everyone to explore genomic science and its impact on research, health and society.
To help researchers to develop their skills and networks, the Institute hosts a range of scientific seminars with internal and invited speakers, scientific group meetings and skills development workshops.
Our Benefits include: Defined Contribution Pension Scheme, Group Income Protection, Healthcare scheme, Childcare Vouchers, Workplace Nursery and 25 days Annual Leave, increasing by one day per year up to a maximum of 30, plus Bank Holidays. We also have a gym, two cafes, dining facilities, and a free campus bus service. Our thriving Sports and Social Club provides many opportunities to meet with people working across the campus.
Wellcome Sanger Institute welcomes applications from all candidates irrespective of age, disability, gender, gender identity, sexual orientation, race, religion or belief, or marital or civil partnership status.
Please include a covering letter and CV with your application. Closing date for applications: 20th February 2018