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Director of Open Targets

Salary in the region of £100,000 - £185,000 plus excellent benefits (Grade PSG1) 

Fixed-term for 5 years

We are seeking a Director of Open Targets to advance the science of target identification, prioritisation and validation.

Open Targets: was launched in 2014 with seed funding from GSK and has expanded into a scientific entity currently with 5 partners (Sanger, EMBL-EBI, GSK, Biogen, Takeda). Open Targets has a portfolio of experimental and bioinformatics platforms and ~90 individuals housed in dedicated space at the Wellcome Genome Campus, Hinxton, Cambridge.

Open Targets combines the skills, knowledge and technologies of its partner organisations, offering a critical mass of expertise that does not exist in any single institution. Large-scale genomic experiments (Sanger Institute) and computational techniques (EMBL-EBI) developed in the public domain are blended with formal pharmaceutical R&D approaches. Experimental data and information generated within the initiative are shared openly to benefit the broader scientific community.

The role will require you to work with the partner organisations to ensure the evolution of an aligned and ambitious strategy with clearly defined goals and milestones. You will sustain and grow Open Targets through recruitment and renewal of industrial partners. You will champion Open Targets approach with the academic and industrial community and develop Open Targets through the recruitment of world-leading scientists and the establishment of additional funding streams.

The role will have an initial five-year tenure however subject to successful review it is envisaged that the role will thereafter be subject to rolling 5-year review.

Job Reference

Essential Skills

Preferred requirements

  • An international reputation as a scientific inspiring leader and impeccable research record relevant to target validation
  • Experience will include a grounding in genetics, genomics, or informatics combined with experience and knowledge to develop and implement strategies to advance human target validation and translational research
  • Proven senior leadership capability
  • Strong background in the use of innovative computational science / genomics / innovative technologies to deliver interpretation of high content human data
  • Experience of creating and leading major multidisciplinary and multinational collaborations and consortia
  • Successful track record in securing extensive funding from internal bodies or external sources (public and private)
  • Demonstrable ability to exercise good judgement in assessing potential research opportunities coupled with the ability to take measured risks
  • Enthusiastic and committed with high energy with the ability to encourage others with their vision
  • Ability to build and maintain positive relationships, both internally and externally
  • Excellent communicator
  • Affinity/knowledge of the drug discovery and development process
  • Experience with industrial collaborations for academic applicants and experience with academic collaborations for applicants from industry

Other information

Our Campus: Set over 125 acres, the stunning and dynamic Wellcome Genome Campus is the biggest aggregate concentration of people in the world working on the common theme of Genomes and BioData. It brings together a diverse and exceptional scientific community, committed to delivering life-changing science with the reach, scale and imagination to solve some of humanity’s greatest challenges.

Positions carry a significant core package of salaries and support with rewarding and flexible employment terms including excellent benefits and relocation support. For more information on our core benefit please visit: Sanger employee benefits.

We seek to provide a supportive family friendly environment to enable scientists at all levels to balance their professional and home lives. This includes options for flexible and part-time working, support and advice for staff taking maternity, paternity, adoption and parental leave an on-site nursery, Campus summer holiday club and childcare voucher scheme.

Genome Research Limited is an Equal Opportunity employer. As part of our dedication to gender equality and promoting women’s careers in science, we hold an Athena SWAN Bronze Award. We will consider all qualified individuals without discrimination on grounds of disability, sexual orientation, pregnancy or maternity leave status, race or national or ethnic origin, age, religion or belief, gender identity or re-assignment, marital or civil partnership status, protected veteran status (if applicable) or any other characteristic protected by law.

For confidential discussions please contact Julia Wilson

Please include a covering letter and CV with your application. Closing date for applications: 24th April 2018