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Computational Postdoctoral Fellow - CASM Programme

Salary £31,503 to £38,030 (dependant on experience) plus excellent benefits

Fixed term for 3 years

A postdoctoral position is available at the Wellcome Sanger Institute (WSI) under the leadership of Dr Peter Campbell as part of the Cancer Genome Project. This is an exciting opportunity for the successful candidate to explore the relationship between accumulation of somatic mutations in normal tissues and the development of cancer, with a focus on understanding the interplay between selective pressures, mutational processes and clonal structure.

The successful applicant will hold a PhD and will have gained significant experience and expertise in large-scale analyses of next-generation sequencing data and the mathematical and statistical modelling of complex data sets. He or she will be part of a multidisciplinary team and will be tasked with proactively seeking and maintaining appropriate collaborations. Successful candidates will also be expected to drive forward the project, working closely with biologists, clinicians and bioinformaticians within and outside the group to accomplish scientific objectives.

Job Reference
83026

Essential Skills

  • A PhD in Genomics, Genetics, Biology (or similar), and a passion for problem solving
  • Extensive experience in a research environment with a well-established publication track record
  • Formal and extensive training in mathematical and statistical analysis of complex data sets
  • Experience in next generation sequencing and the analysis of sequencing data
  • The ability to effectively communicate with collaborators and occasionally present oral communication to large groups
  • Proven independent working style, technical problem solving, data analysis and generation of novel ideas

Ideal Skills

  • An understanding, experience and published outcomes from analysing and interpreting large datasets using at least one statistical package (e.g. R/SPLUS, SAS) and experience in programming (e.g. Perl, Python, C++, Java) 
  • Experience in genomics approaches and in method development 

Other information

The Wellcome Sanger Institute is a charitably funded research centre and committed to training the next generation of genome scientists. Focused on understanding the role of genetics in health and disease and a world leader in the genomic revolution, our mission is to use genome sequences to advance understanding of human and pathogen biology in order to improve human health. We aim to provide results that can be translated into diagnostics, treatments or therapies that reduce global health burdens. Our science is large-scale and organised into Programmes, led by our Faculty who conceive and deliver our science, and supported by our Scientific Operations teams responsible for all data production pipelines at the Institute. 

Our Campus: Set over 125 acres, the stunning and dynamic Wellcome Genome Campus is the biggest aggregate concentration of people in the world working on the common theme of Genomes and BioData. It brings together a diverse and exceptional scientific community, committed to delivering life-changing science with the reach, scale and imagination to pursue some of humanity’s greatest challenges.

Our Benefits: Our employees have access to a comprehensive range of benefits and facilities including:

  • Group Defined Contribution Pension Scheme and Life Assurance
  • Group Income Protection
  • Private Health Insurance
  • 25 days annual leave, increasing by one day a year to a maximum of 30
  • Family friendly environment including options for flexible and part-time working, a childcare voucher scheme, Campus Nursery and Summer holiday club
  • Two days paid Employee Volunteering Leave a year
  • Employee Discount Scheme
  • Campus Gym, tennis courts, cricket pitch and sports hall plus a range of dining facilities
  • Active Campus Sports and Social Club
  • Free Campus Bus Service

Genome Research Limited is an Equal Opportunity employer. As part of our commitment to equality, diversity and inclusion and promoting equality in careers in science, we hold an Athena SWAN Bronze Award and have an active Equality, Diversity and Inclusion programme of activity. We will consider all applicants without discrimination on grounds of disability, sexual orientation, pregnancy or maternity leave status, race or national or ethnic origin, age, religion or belief, gender identity or re-assignment, marital or civil partnership status, protected veteran status (if applicable) or any other characteristic protected by law. We are open to a range of flexible working options including part-time or full-time employment as well as flexible hours due to caring or other commitments.

Please include a covering letter and CV with your application.   

Closing date for applications: 21st May 2018; however applications will be considered and reviewed on an on-going basis and therefore the post may be filled before the deadline.