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Senior Staff Scientist - DNA Pipelines

Salary range £43,722 to £52,903 plus benefits

We are looking to recruit two Senior Staff Scientists into the DNA Pipelines Development team. You will be joining the Institute into an exciting and challenging role with growth potential. The types of projects you could be working on are varied, requiring a wide range of disciplines and might would suit individuals with molecular biology, genetics, biochemistry, single cell biology and/or high throughput liquid handling and laboratory automation backgrounds.

You will be a creative, highly motivated and productive scientist who will drive research and development programs to create innovative, streamlined and cost effective high throughput protocols, to design and optimize novel strategies, and perform ground-breaking experiments on the very latest next-generation DNA sequencing platforms and other scientific operations services. You will devise work programs, build excellent working relationships and collaborations to achieve project aims, influence project stakeholders, and be the “go to” person for your projects.

As a Senior Staff Scientist you will take full responsibility for the complete lifecycle of diverse projects requiring significant independent working; driving, managing and delivering R&D projects across a diverse range of disciplines. 

You should have a proven track record of method development and be able to demonstrate independent conceptual and critical thinking that could result in the creation of new applications and processes.

Job Reference

Essential Skills

  • Ph.D. degree in a biological science (or Masters degree with significant experience in the field).
  • A recognized expert with considerable and demonstrable proficiency in molecular biology and a clear track record in the field.
  • Proven ability to independently develop and optimize new scientific methods.
  • Knowledge and experience of next­ generation DNA sequencing and/or high-­throughput bioinformatics.
  • Ability to develop and optimize new scientific methods.
  • Proven ability to work independently with an adaptable and enthusiastic approach.
  • Ability to work effectively as a team player
  • Ability to create ideas, initiate a program of work and draw conclusions.
  • Strong interpersonal skills with ability to influence negotiate and build positive relationships.
  • Excellent communication at all levels, including oral presentation, scientific writing skills, and active listening.
  • Ability to communicate complex scientific concepts in a clear and concise manner.
  • High degree of fluency in IT skills, software, automation and robotics.
  • Ability to teach, train and transition new concepts and methods.
  • Excellent analytical and troubleshooting skills.
  • Excellent organizational and record keeping skills.
  • Motivated with a strong resolve to complete projects with strong attention to detail


Ideal Skills

  • Practical and theoretical understanding of DNA sequencing, genotyping, DNA extraction, nucleic acid preparation, liquid handling, single cell genomics would be advantageous but by no means an essential requirement.
  • Knowledge of writing and developing laboratory automation.
  • Experience in the application of bioinformatics tools.
  • Demonstrable appreciation of production practices including process engineering and six­ sigma principles.
  • Experience with liquid handling automation platforms especially in writing scripts and optimising processes on Agilent Bravo, Hamilton and/or nanovolume dispensing platforms
  • Project management experience/skills 

Other information

Our mission is to use genome sequences to advance understanding of human and pathogen biology in order to improve human health. We aim to provide results that can be translated into diagnostics, treatments or therapies that reduce global health burdens. Our science is large-scale and organised into Programmes, led by our Faculty who conceive and deliver our science, and supported by our Scientific Operations teams responsible for all data production pipelines at the Institute.

Our Campus: Set over 125 acres, the stunning and dynamic Wellcome Genome Campus is the biggest aggregate concentration of people in the world working on the common theme of Genomes and BioData. It brings together a diverse and exceptional scientific community, committed to delivering life-changing science with the reach, scale and imagination to solve some of humanity’s greatest challenges.  

The Campus is a community of organisations working in genomic research, enterprise, education and discourse. It is home to some of the world's foremost institutes and organisations in genomics and computational biology, including the Wellcome Trust Sanger Institute which is the largest organisation on Campus, the European Bioinformatics Institute (EMBL-EBI), Open Targets and Genomics England.  Also located here is Connecting Science - its mission is to enable everyone to explore genomic science and its impact on research, health and society by drawing on the ground-breaking research taking place on the Campus.

Genome Research Limited is an Equal Opportunity employer. As part of our commitment to equality, diversity and inclusion and promoting equality in careers in science, we hold an Athena SWAN Bronze Award and have an active Equality, Diversity and Inclusion programme of activity. We will consider all applicants without discrimination on grounds of disability, sexual orientation, pregnancy or maternity leave status, race or national or ethnic origin, age, religion or belief, gender identity or re-assignment, marital or civil partnership status, protected veteran status (if applicable) or any other characteristic protected by law. We are open to a range of flexible working options including part-time or full-time employment as well as flexible hours due to caring or other commitments. 

Closing Date for applications: 17th May 2018