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Postdoctoral Fellow in Statistical and Computational Genomics

Salary in the region of £31,503 - £39,492 (dependent on experience) plus excellent benefits

Fixed term contract for 3 years

A postdoctoral position is available in the Wellcome Sanger Institute under the leadership of Dr Daniel Gaffney. The main research focus of our group is to understand how genetic variants influence cellular functions, using a mixture of statistical genetics, machine learning and high throughput functional genomics data. This post will focus on applications of single sequencing to problems in genetic mapping, in particular to cellular model systems based on human induced pluripotent stem cells. The post-holder will also have access to unique, large-scale functional genomics data sets generated human induced pluripotent stem cells that our group has developed as part of the Human Induced Pluripotent Stem Cells Initiative.

Candidates in Biology with a background in quantitative analysis and population genetics are strongly encouraged to apply. We also welcome candidates with a background in Physics, Statistics or Computer Science with strong interests in computational biology. Excellent programming skills, experience with very large data sets and an ability to work as part of a team are essential. The post-holder will work as part of the Gaffney group at WSI, for more information on the group’s research see:

http://www.sanger.ac.uk/science/groups/gaffney-group

The goal of our lab is to understand how regulatory variants alter cellular phenotypes using a variety of experimental and computational approaches. The Wellcome Sanger Institute offers a world-class academic environment, access to cutting edge sequencing facilities and extensive expertise in genome analysis and human genetics.

Postdoctoral Fellows are typically in their first or second postdoctoral position as part of a period of early career research training. Successful applicant(s) who have submitted their PhD thesis and are awaiting their PhD award are encouraged to apply. This position is initially for a fixed term of 3 years. For further information please contact Daniel Gaffney on dg13@sanger.ac.uk.

Job Reference
83046
Documents

Essential Skills

  • PhD in a relevant subject area (Computational Biology, Population Genetics/Genomics, Computer Science, Physics)
  • Strong publishing record
  • Strong statistical and quantitative skills and familiarity with statistical modeling and software
  • Excellent programming skills and extensive experience of UNIX/Linux and cluster computing
  • Ability to communicate ideas and results effectively
  • Ability to work well with other team members
  • Ability to work to tight deadlines

Ideal Skills

  • Previous experience in population genetic analysis
  • Experience with analysis of -omics data sets
  • Some familiarity with the stem cell biology

Other information

The Wellcome Sanger Institute is a charitably funded research centre and committed to training the next generation of genome scientists. Focused on understanding the role of genetics in health and disease and a world leader in the genomic revolution, our mission is to use genome sequences to advance understanding of human and pathogen biology in order to improve human health. We aim to provide results that can be translated into diagnostics, treatments or therapies that reduce global health burdens. Our science is large-scale and organised into Programmes, led by our Faculty who conceive and deliver our science, and supported by our Scientific Operations teams responsible for all data production pipelines at the Institute.

Our Campus: Set over 125 acres, the stunning and dynamic Wellcome Genome Campus is the biggest aggregate concentration of people in the world working on the common theme of Genomes and BioData. It brings together a diverse and exceptional scientific community, committed to delivering life-changing science with the reach, scale and imagination to pursue some of humanity’s greatest challenges.

Our Benefits: Our employees have access to a comprehensive range of benefits and facilities including:

  • Group Defined Contribution Pension Scheme and Life Assurance
  • Group Income Protection
  • Private Health Insurance
  • 25 days annual leave, increasing by one day a year to a maximum of 30
  • Family friendly environment including options for flexible and part-time working, a childcare voucher scheme, Campus Nursery and Summer holiday club
  • Two days paid Employee Volunteering Leave a year
  • Employee Discount Scheme
  • Campus Gym, tennis courts, cricket pitch and sports hall plus a range of dining facilities
  • Active Campus Sports and Social Club
  • Free Campus Bus Service

Genome Research Limited is an Equal Opportunity employer. As part of our commitment to equality, diversity and inclusion and promoting equality in careers in science, we hold an Athena SWAN Bronze Award and have an active Equality, Diversity and Inclusion programme of activity. We will consider all applicants without discrimination on grounds of disability, sexual orientation, pregnancy or maternity leave status, race or national or ethnic origin, age, religion or belief, gender identity or re-assignment, marital or civil partnership status, protected veteran status (if applicable) or any other characteristic protected by law. We are open to a range of flexible working options including part-time or full-time employment as well as flexible hours due to caring or other commitments.

Please include a covering letter and CV with your application.  Closing date: 27th May 2018