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Postdoctoral Fellow (Computational) - Hemberg Group

Salary in the region of £31,503 - £39,492 (dependent on experience) plus excellent benefits

Fixed term for 2 years

The Hemberg group is primarily interested in developing quantitative methods and models for analysing gene expression and gene regulation. We are particularly interested in working with data generated from high-throughput technologies, making sure that the software used to analyse this data is computationally and statistically rigorous. We are looking to appoint a computational post-doctoral fellow who is interested in applying their skills to transcriptomics and genomics. Prior experience of working with next-generation sequencing data is not necessary. We are looking for someone with strong mathematical and/or programming skills who is willing to learn about problems in molecular biology.

  • To carry out development of computational methods for analysis of high throughput genomics data, with a focus on single-cell analysis or regulatory genomics
  • To plan a programme of research that is original but fits within the general research area of the team, taking into account the relevant literature, own experience, and advice from the team leader and other appropriate scientists
  • To carry out the research, developing the practical skills required for successful completion
  • To analyse data and write up results for publication, and to deal with all aspects
  • of the publication process
  • To communicate the results through other relevant means, such as talking or presenting posters at scientific meetings
  • To seek appropriate training, including taking an active part in any training programmes organised for postdoctoral training fellows. This will include transferable skills training
  • To take a full part in the general duties of the team, and to pass on skills and knowledge to other team members and visitors. To take part in wider Sanger Institute activities as appropriate
  • To complete training period in a timely manner, publish the research and document any unpublished data and materials before moving on to a new position

The post-holder will work as part of the Hemberg group at WSI, for more information on the group’s research see:

Postdoctoral Fellows are typically in their first or second postdoctoral position as part of a period of early career research training. Successful applicant(s) who have submitted their PhD thesis and are awaiting their PhD award are encouraged to apply. This position is initially for a fixed term of 2 years. For further information please contact Martin Hemberg on

Job Reference

Essential Skills

  • PhD (or equivalent) in Quantitative Biology, Mathematics, Physics or Computer Science 
  • Ability to independently solve complex scientific/technical problems and manage scientific projects 
  • Programming skills (e.g. R, C, Python, Julia, Java, Matlab) 
  • Mathematical modelling or machine learning 
  • Excellent communication skills 
  • Self-motivation and diligence 
  • Good publication track record

Ideal Skills

  • Ability to train and develop others in scientific techniques, including working with an international interdisciplinary group of scientists 
  • Experience with cloud computing

Other information

The Wellcome Sanger Institute is a charitably funded research centre and committed to training the next generation of genome scientists. Focused on understanding the role of genetics in health and disease and a world leader in the genomic revolution, our mission is to use genome sequences to advance understanding of human and pathogen biology in order to improve human health. We aim to provide results that can be translated into diagnostics, treatments or therapies that reduce global health burdens. Our science is large-scale and organised into Programmes, led by our Faculty who conceive and deliver our science, and supported by our Scientific Operations teams responsible for all data production pipelines at the Institute.

Our Campus: Set over 125 acres, the stunning and dynamic Wellcome Genome Campus is the biggest aggregate concentration of people in the world working on the common theme of Genomes and BioData. It brings together a diverse and exceptional scientific community, committed to delivering life-changing science with the reach, scale and imagination to pursue some of humanity’s greatest challenges.

Our Benefits: Our employees have access to a comprehensive range of benefits and facilities including:

  • Group Defined Contribution Pension Scheme and Life Assurance
  • Group Income Protection
  • Private Health Insurance
  • 25 days annual leave, increasing by one day a year to a maximum of 30
  • Family friendly environment including options for flexible and part-time working, a childcare voucher scheme, Campus Nursery and Summer holiday club
  • Two days paid Employee Volunteering Leave a year
  • Employee Discount Scheme
  • Campus Gym, tennis courts, cricket pitch and sports hall plus a range of dining facilities
  • Active Campus Sports and Social Club
  • Free Campus Bus Service

Genome Research Limited is an Equal Opportunity employer. As part of our commitment to equality, diversity and inclusion and promoting equality in careers in science, we hold an Athena SWAN Bronze Award and have an active Equality, Diversity and Inclusion programme of activity. We will consider all applicants without discrimination on grounds of disability, sexual orientation, pregnancy or maternity leave status, race or national or ethnic origin, age, religion or belief, gender identity or re-assignment, marital or civil partnership status, protected veteran status (if applicable) or any other characteristic protected by law. We are open to a range of UK-based flexible working options including part-time or full-time employment as well as flexible hours due to caring or other commitments.

Please include a covering letter and CV with your application.  Closing date: 23rd May 2018however applications will be considered and reviewed on an on-going basis and therefore the post may be filled before the deadline.