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Senior Bioinformatician

Salary £36,373 to £44,011 plus excellent benefits

Permanent / Open Contract

We are looking for a talented and highly motivated data scientist/ bioinformatician to be part of the Teichmann’s lab research, aiming to understand the functions of the human body at the single cell level. Recent technological advances have meant that we can now profile large number of cells at the single cell level, generating very large genomics data sets which can be mined for exciting new insights into how the immune system and the human body works.

The Teichmann group is based at the Sanger Institute, Hinxton. Our laboratory comprises an international, collaborative team of both experimental and computational scientists. Our computational team applies existing bioinformatics packages to interpret our data and also develops new tools that are able to cope with challenges arising from newly developed single cell genomics techniques. The Teichmann lab has been at the forefront of this fast-moving field, making significant contributions in providing computational tools and gaining insights into immunology, with a particular emphasis in T cell biology.

In our laboratory, you will work closely with scientists from within the Teichmann lab, as well as the Human Cell Atlas team, whose ultimate aim is to characterise every cell type in the human body as a reference for future study and treatment of diseases. There are also close interactions with members of the European Bioinformatics Institute which is also based at the Wellcome Genome Campus.

As part of Teichmann lab, you will bring your bioinformatics or data science expertise to implement computational projects, set up data bases to store experimental data and meta data used by the lab and maintain these systems. This may include the setting up of web interfaces for external users of the data. You will run and maintain the internal IT services (software, databases, websites), with an opportunity to improve the existing IT systems where required. The requirements of the lab stretch from support in laboratory automation, to lab tracking, data processing and visualization.  On a day-to-day basis, you will support researcher to facilitate storage, access and security of experimental data.

We are looking for a person, who enjoys team work and interacts well with others, ranging from collaborating clinicians and scientists, to post-docs, students and research assistants. Good communications skills will also be required to represent the group on relevant committees and potentially externally at conferences and meetings.

The Wellcome Sanger Institute operates at the forefront of genomics, sequencing and analyses targeting a wide range of genomes from single cell pathogens to higher vertebrates, with an emphasis on genomes relevant to human medicine and welfare (  The Teichmann lab is part of the Cellular Genetics Programme, with particular strengths in single cell genomics and computations analysis. The Human Cell Atlas is a new initiative, spanning many laboratories across the world. The Sanger Institute will be a key player in delivering this exciting project.  

Job Reference

Essential Skills

  • Degree in computer science, bioinformatics or a scientific discipline
  • Competency in programming languages e.g., Java, Python, Perl, R
  • Ability to learn new programming languages as required
  • Familiarity with developing in a UNIX/Linux environment
  • Experience using and developing databases, e.g., Oracle, MySql
  • Experience in web development
  • Interest in bioinformatics and molecular biology
  • Ability to work with others in a collegiate manner
  • Ability to work independently to efficiently meet deadlines
  • Ability to work independently or as part of a larger team
  • Ability to communicate effectively internally at all levels and with select external individuals
  • Able to present internally

Ideal Skills

  • MSc in Computer Science, Bioinformatics or related field
  • Experience of molecular biology/other biological fields
  • Experience of statistical analyses
  • Experience of analysing complex data sets
  • Experience of developing analytical pipelines
  • Experience of running code in high performance computing environments

Other information

The Wellcome Sanger Institute is a charitably funded research centre and committed to training the next generation of genome scientists. Focused on understanding the role of genetics in health and disease and a world leader in the genomic revolution, our mission is to use genome sequences to advance understanding of human and pathogen biology in order to improve human health. We aim to provide results that can be translated into diagnostics, treatments or therapies that reduce global health burdens. Our science is large-scale and organised into Programmes, led by our Faculty who conceive and deliver our science, and supported by our Scientific Operations teams responsible for all data production pipelines at the Institute.

Our Campus: Set over 125 acres, the stunning and dynamic Wellcome Genome Campus is the biggest aggregate concentration of people in the world working on the common theme of Genomes and BioData. It brings together a diverse and exceptional scientific community, committed to delivering life-changing science with the reach, scale and imagination to pursue some of humanity’s greatest challenges.

Our Benefits: Our employees have access to a comprehensive range of benefits and facilities including:

  • Group Defined Contribution Pension Scheme and Life Assurance
  • Group Income Protection
  • Private Health Insurance
  • 25 days annual leave, increasing by one day a year to a maximum of 30
  • Family friendly environment including options for flexible and part-time working, a childcare voucher scheme, Campus Nursery and Summer holiday club
  • Two days paid Employee Volunteering Leave a year
  • Employee Discount Scheme
  • Campus Gym, tennis courts, cricket pitch and sports hall plus a range of dining facilities
  • Active Campus Sports and Social Club
  • Free Campus Bus Service

Genome Research Limited is an Equal Opportunity employer. As part of our commitment to equality, diversity and inclusion and promoting equality in careers in science, we hold an Athena SWAN Bronze Award and have an active Equality, Diversity and Inclusion programme of activity. We will consider all applicants without discrimination on grounds of disability, sexual orientation, pregnancy or maternity leave status, race or national or ethnic origin, age, religion or belief, gender identity or re-assignment, marital or civil partnership status, protected veteran status (if applicable) or any other characteristic protected by law. We are open to a range of UK-based flexible working options including part-time or full-time employment as well as flexible hours due to caring or other commitments.

Please include a covering letter and CV with your application.

Closing date: 10th June 2018however applications will be considered and reviewed on an on-going basis and therefore the post may be filled before the deadline.