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Advanced Research Assistant - Cellular Generation and Phenotyping

Salary in the region of £26,693 - £28,500 depending on experience plus benefits 

We are looking for an enthusiastic, highly motivated individual to join a team of scientists working on the delivery of large scale cell biology projects as an Advanced Research Assistant.

You will be working on The Human Cell Atlas project as well as hold other responsibilities which will aid in the development and running of the department.

A key focus in your role will be to develop skills and experience in human tissue processing, cryo sectioning and paraffin sectioning of human tissue samples; spatial transcriptomics and RNAScope methods. Experience in these areas is highly desirable but training will be provided on all methods, transitioning into delivering the protocols without requiring close supervision.

This is an excellent opportunity for a motivated and adaptable individual to support the cutting edge science delivered within Cellular Generation and Phenotyping.

The department of Cellular Generation and Phenotyping (CGaP) is a core facility whose role is to carry forward the Science at the Sanger Institute and run several large scale cell biology projects at a time.  Projects currently running in the department include the Human Cell Atlas, genome wide CRISPR screens, induced pluripotent stem cell derivation and differentiation into a variety of different lineages, organoid derivation and generation of P. Falciparum mutants.

Some on call out of hours work may be required. 

Job Reference
83113

Essential Skills

  • Degree in Biological Sciences, or equivalent qualification 
  • Relevant laboratory experience 
  • Extensive experience working with primary tissues and/or cell lines 
  • Prior experience of running tissue or primary cell based assays or antibody staining techniques 
  • Proven process improvement/troubleshooting ability  
  • Good written and oral communication skills 
  • Computer literate 
  • Ability to keep good up-to-date records with attention to detail 
  • Ability to test and implement new approaches and techniques into new SOPs
  • Ability to work to a schedule and successfully manage and prioritise multiple competing tasks 
  • Proven experience of working within a team 
  • Excellent organisational and communication skills 

Ideal Skills

  • Experience of training others 
  • Proven track record in generating and analysing large volumes of high quality data 
  • Cryosectioning experience 
  • Other histology experience e.g. wax embedding / paraffin sectioning / H&E staining / immunohistochemistry 
  • Experience working with human tissue samples / Human Tissue Act 

Other information

Please include a covering letter with your application describing how you meet the essential criteria for the role.

Closing date for applications is 27th June 2018

Interview will take place early July. 

The Wellcome Sanger Institute is a charitably funded research centre and committed to training the next generation of genome scientists. Focused on understanding the role of genetics in health and disease and a world leader in the genomic revolution, our mission is to use genome sequences to advance understanding of human and pathogen biology in order to improve human health. We aim to provide results that can be translated into diagnostics, treatments or therapies that reduce global health burdens. Our science is large-scale and organised into Programmes, led by our Faculty who conceive and deliver our science, and supported by our Scientific Operations teams responsible for all data production pipelines at the Institute.

Our Campus: Set over 125 acres, the stunning and dynamic Wellcome Genome Campus is the biggest aggregate concentration of people in the world working on the common theme of Genomes and BioData. It brings together a diverse and exceptional scientific community, committed to delivering life-changing science with the reach, scale and imagination to pursue some of humanity’s greatest challenges.

Our Benefits: Our employees have access to a comprehensive range of benefits and facilities including:

  • Group Defined Contribution Pension Scheme and Life Assurance
  • Group Income Protection
  • Private Health Insurance
  • 25 days annual leave, increasing by one day a year to a maximum of 30
  • Family friendly environment including options for flexible and part-time working, a childcare voucher scheme, Campus Nursery and Summer holiday club
  • Two days paid Employee Volunteering Leave a year
  • Employee Discount Scheme
  • Campus Gym, tennis courts, cricket pitch and sports hall plus a range of dining facilities
  • Active Campus Sports and Social Club
  • Free Campus Bus Service

Genome Research Limited is an Equal Opportunity employer. As part of our commitment to equality, diversity and inclusion and promoting equality in careers in science, we hold an Athena SWAN Bronze Award and have an active Equality, Diversity and Inclusion programme of activity. We will consider all applicants without discrimination on grounds of disability, sexual orientation, pregnancy or maternity leave status, race or national or ethnic origin, age, religion or belief, gender identity or re-assignment, marital or civil partnership status, protected veteran status (if applicable) or any other characteristic protected by law. We are open to a range of UK-based flexible working options including part-time or full-time employment as well as flexible hours due to caring or other commitments.