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Staff Scientist or Postdoctoral Fellow - Cancer Microbiota Interactions

Staff Scientist £36,373 - £44,011 or Postdoctoral Fellow £31,503 - £38,755  –Cancer-Microbiota Interactions plus excellent benefits

We are seeking a talented, motivated and experienced Staff Scientist or Postdoctoral Fellow to work at the Wellcome Sanger Institute on immune system-microbiota interactions under the leadership of Dr Trevor Lawley ( and Dr David Adams (  We are expanding our germ free/gnotobiotic capabilities and are looking for a Scientist to lead the development of mouse models to understand how the human microbiota influences health and immunity. This position would be ideal for someone who recently completed postdoctoral training and has a strong background in mouse biology with a focus on such areas as immunology, metabolism, cancer biology or vaccinology.

This is an exciting opportunity for the successful candidate to join a dynamic team investigating the role of the microbiota in a variety of diseases, such as infections, cancers and immunotherapy using clinical samples, genomics, microbiology and model organisms. There is a strong translational focus with the goal of developing novel, microbiome-based diagnostics and therapeutics.

The successful applicant will have experience in designing and performing mouse experiments and analysis of the immune system using approaches such as flow-cytometry, transcriptomics and immunophenotyping to identify human commensal bacteria with immunomodulatory properties.  The post-holder will be part of a multidisciplinary, collaborative team and will be expected to work closely with existing team members to accomplish scientific objectives and proactively identify, establish and develop new collaborations and drive publications.

**please note: discussions will take place during the interview process as to which role profile you are being considered for.

Job Reference

Essential Skills

  • PhD with strong background in mouse immunology, genetics, infection biology, vaccinology or cancer models
  • Degree in Biological Sciences, or equivalent qualification or experience 
  • Experience of working with animal models 
  • Supervisory/coaching experience 
  • Good publication record 
  • Experience of planning research projects 
  • Ability to organise own workload and that of team 
  • High level of trouble shooting skills 
  • Good presentation skills 
  • Experience in supervising, training and guiding others 
  • Holds a Personal Home Office License Modules 1 – 3 
  • Institute of Animal Technology Certificate or equivalent 
  • Awareness of A[SP]A and Refinement, Replacement & Reduction 
  • Ability to keep neat and accurate records 


Ideal Skills

  • Experience of working with Germ Free Model Organisms 
  • Experience presenting to outside groups 
  • Laboratory Containment Level 2 experience 
  • Experience writing COSHH assessments and Biological Risk Assessments 


Other information

The Wellcome Sanger Institute is a charitably funded research centre and committed to training the next generation of genome scientists. Focused on understanding the role of genetics in health and disease and a world leader in the genomic revolution, our mission is to use genome sequences to advance understanding of human and pathogen biology in order to improve human health. We aim to provide results that can be translated into diagnostics, treatments or therapies that reduce global health burdens. Our science is large-scale and organised into Programmes, led by our Faculty who conceive and deliver our science, and supported by our Scientific Operations teams responsible for all data production pipelines at the Institute.

Our Campus: Set over 125 acres, the stunning and dynamic Wellcome Genome Campus is the biggest aggregate concentration of people in the world working on the common theme of Genomes and BioData. It brings together a diverse and exceptional scientific community, committed to delivering life-changing science with the reach, scale and imagination to pursue some of humanity’s greatest challenges.

Our Benefits: Our employees have access to a comprehensive range of benefits and facilities including:

  • Group Defined Contribution Pension Scheme and Life Assurance
  • Group Income Protection
  • Private Health Insurance
  • 25 days annual leave, increasing by one day a year to a maximum of 30
  • Family friendly environment including options for flexible and part-time working, a childcare voucher scheme, Campus Nursery and Summer holiday club
  • Two days paid Employee Volunteering Leave a year
  • Employee Discount Scheme
  • Campus Gym, tennis courts, cricket pitch and sports hall plus a range of dining facilities
  • Active Campus Sports and Social Club
  • Free Campus Bus Service

Genome Research Limited is an Equal Opportunity employer. As part of our commitment to equality, diversity and inclusion and promoting equality in careers in science, we hold an Athena SWAN Bronze Award and have an active Equality, Diversity and Inclusion programme of activity. We will consider all applicants without discrimination on grounds of disability, sexual orientation, pregnancy or maternity leave status, race or national or ethnic origin, age, religion or belief, gender identity or re-assignment, marital or civil partnership status, protected veteran status (if applicable) or any other characteristic protected by law. We are open to a range of UK-based flexible working options including part-time or full-time employment as well as flexible hours due to caring or other commitments.

Please include a covering letter and CV with your application. Closing date: 13th January 2019