Postdoctoral Fellow (Vento Faculty, Cellular Genetics)

Salary in the region of £31,897 - £39,240 (dependent on experience) plus excellent benefits

Fixed term for 3 years

We are looking to appoint a highly motivated postdoctoral fellow in immunogenomics, developmental transcriptomics and genetics to join Roser Vento-Tormo’s group at the Wellcome Sanger Institute.

The primary objective is to use genomics, spatial transcriptomics and in vitro assays to map the immune responses against infection across the lifespan. Specifically, the candidate will develop wet and dry techniques to map the communication events during infection and their consequences for fetal development and adult health.

The primary activities will be: i) Acquire material from tissue repositories and coordinate with collaborators to perform wet lab aspects of genomics, spatial transcriptomics and in vitro assays; ii) Perform data analysis of single cell RNA-seq data in collaboration with other team members. The postdoctoral fellow will take the research to conclusion via publication of data in the form of manuscripts and presentations at conferences.

Our lab is also involved in a wide variety of other projects ranging from building a map of the reproductive organs to the development of computational methods to map cell-cell communication ( While the work will be focused on immune response to infection, as key part of our group you will have the opportunity to make important contributions to the full range of research our group is engaged in. In addition, you will be supported to develop your own research projects within the scope of the group’s interests.

This is primarily a training post, with associated responsibility of the faculty team leader and Sanger Institute to ensure training is delivered.

This role may involve occasional work out-of-hours due to the nature of tissue availability. 

Job Reference

Essential Skills

  • PhD in a relevant subject area (e.g. Immunology, Developmental Biology, Genomics, Molecular Biology)
  • Expertise in at least one scripting language (R, Python)
  • Experience of planning research projects
  • Excellent communication skills to allow efficient interactions with collaborators
  • Experimental troubleshooting skills
  • Experience of writing manuscripts for publication
  • Ability to work within a team

Ideal Skills

  • Understanding of ethics of working with human tissue samples 
  • Experience with organoids
  • Experience in histology
  • Experience with image data analysis

Other information

The Wellcome Sanger Institute is a charitably funded research centre and committed to training the next generation of genome scientists. Focused on understanding the role of genetics in health and disease and a world leader in the genomic revolution, our mission is to use genome sequences to advance understanding of human and pathogen biology in order to improve human health. We aim to provide results that can be translated into diagnostics, treatments or therapies that reduce global health burdens. Our science is large-scale and organised into Programmes, led by our Faculty who conceive and deliver our science, and supported by our Scientific Operations teams responsible for all data production pipelines at the Institute. 

Our Campus: Set over 125 acres, the stunning and dynamic Wellcome Genome Campus is the biggest aggregate concentration of people in the world working on the common theme of Genomes and BioData. It brings together a diverse and exceptional scientific community, committed to delivering life-changing science with the reach, scale and imagination to pursue some of humanity’s greatest challenges.

Our Benefits: Our employees have access to a comprehensive range of benefits and facilities including:

  • Group Defined Contribution Pension Scheme and Life Assurance
  • Group Income Protection
  • Private Health Insurance
  • 25 days annual leave, increasing by one day a year to a maximum of 30
  • Family friendly environment including options for flexible and part-time working, a childcare voucher scheme, Campus Nursery and Summer holiday club
  • Two days paid Employee Volunteering Leave a year
  • Employee Discount Scheme
  • Campus Gym, tennis courts, cricket pitch and sports hall plus a range of dining facilities
  • Active Campus Sports and Social Club
  • Free Campus Bus Service

Genome Research Limited hold an Athena SWAN Bronze Award and will consider all individuals without discrimination and are committed to creating an inclusive environment for all employees, where everyone can thrive.

Please include a covering letter and CV with your application. Closing date for applications: 25th February 2019