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Postdoctoral Fellow - Immunology / Infection Biology

Salary range: £31,897 to £39,986 depending on experience

Fixed term for 3 years

We are looking for a postdoctoral scientist interested in discovering novel mechanisms of immunoregulation by malaria-causing Plasmodium parasites. The Cell Surface Signalling Laboratory at the Wellcome Sanger Institute led by Dr Gavin Wright uses systematic protein-based approaches to identify extracellular receptor-ligand interactions that are important for infection with the ultimate aim of identifying new interventions and therapeutic targets.

The project will involve refining and implementing innovative biochemical and cellular methods to deepen our molecular understanding of how Plasmodium parasites interact with their mammalian hosts. The primary objective will be to identify novel host-pathogen receptor-ligand interactions using established high throughput technologies developed in the laboratory and to determine their functional role. We are particularly interested to hear from candidates with experience in basic immunological mechanisms who are interested in applying these at the interface of host-pathogen interactions.

For informal discussion, please contact Gavin Wright (

Job Reference

Essential Skills

  • PhD in immunology and/or infection biology
  • Strong molecular biology skills
  • Outstanding communication skills, to ensure good interactions across multiple research teams; able to communicate effectively about complex technical matters with both experts and non-experts
  • Excellent organisation and record keeping skills
  • Ability to deliver high-quality scientific outputs
  • Ability to work in a team

Ideal Skills

  • Cell culture, recombinant protein expression and purification
  • Cell-based immunological assays
  • Flow cytometry

Other information

The Wellcome Sanger Institute is a charitably funded research centre and committed to training the next generation of genome scientists. Focused on understanding the role of genetics in health and disease and a world leader in the genomic revolution, our mission is to use genome sequences to advance understanding of human and pathogen biology in order to improve human health. We aim to provide results that can be translated into diagnostics, treatments or therapies that reduce global health burdens. Our science is large-scale and organised into Programmes, led by our Faculty who conceive and deliver our science, and supported by our Scientific Operations teams responsible for all data production pipelines at the Institute. 

Our Campus: Set over 125 acres, the stunning and dynamic Wellcome Genome Campus is the biggest aggregate concentration of people in the world working on the common theme of Genomes and BioData. It brings together a diverse and exceptional scientific community, committed to delivering life-changing science with the reach, scale and imagination to pursue some of humanity’s greatest challenges.

Our Benefits: Our employees have access to a comprehensive range of benefits and facilities including:

  • Defined Contribution Pension Scheme and Life Assurance
  • Group Income Protection
  • Private Health Insurance
  • 25 days annual leave, increasing by one day a year to a maximum of 30
  • Family friendly environment including options for flexible and part-time working, a childcare voucher scheme, Campus Nursery and Summer holiday club
  • Two days paid Employee Volunteering Leave a year
  • Employee Discount Scheme
  • Campus Gym, tennis courts, cricket pitch and sports hall plus a range of dining facilities
  • Active Campus Sports and Social Club
  • Free Campus Bus Service

Genome Research Limited hold an Athena SWAN Bronze Award and will consider all individuals without discrimination and are committed to creating an inclusive environment for all employees, where everyone can thrive.

Please include a covering letter and CV with your application. Closing date for applications: 22nd April 2019