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Advanced Research Assistant - Vento Faculty, Cellular Genetics

Salary in the region of £26,960 - £32,622 (dependent on experience) plus excellent benefits

Fixed term for 18 Months

The Vento-Tormo Group is currently looking for an enthusiastic, highly motivated and technically skilled Advanced Research Assistant depending on experience to work in the MRC-Human cell atlas funded female reproductive atlas (ventolab.org).

You will carry out both routine and more bespoke laboratory protocols and procedures including but not limited to: RNA/DNA NGS library preparation; tissue dissociation techniques and spatial transcriptomics methods. Training will be provided when necessary. The Wellcome Sanger Institute conducts cutting edge genomic research on an unprecedented scale and our laboratory teams play a vital role in enabling and supporting our science.

Working as part of the dynamic multi-disciplinary team the selected candidate will be helping to provide laboratory solutions and support in diverse projects.

You will be able to work independently, have good communication skills and interact well with the team. You will be expected to take a collaborative and pragmatic approach when planning the work schedules in order to prioritise effectively.

Job Reference
83450

Essential Skills

  • Biological degree with relevant laboratory experience
  • Good written and oral communication skills
  • Excellent organisational and communication skills
  • Ability to keep good records 
  • Good sample management; tracking, labelling and storage of samples
  • Experience in histology
  • Significant experience of core molecular biology techniques, including sample handling, PCR, RNA/DNA purification, library prep and similar
  • Good Laboratory Practice
  • Ability to test and implement new approaches and techniques
  • Computer literate
  • Ability to work to a schedule and successfully manage and prioritise multiple competing projects
  • Ability to organise own workload
  • Ability to work independently and within a group but be able to recognise when to seek help

Ideal Skills

  • Experience working with human tissue samples / Human Tissue Act
  • Experience in fluorescent microscopy
  • Experience in histology (in situ hybridization and immunohistochemistry)
  • Knowledge of single-cell sequencing technologies
  • Experience in immune cell assays such as FACS
  • Experience with protocols relevant to genomics of gene expression and gene regulation including chromatin immunoprecipitation (ChIP), and ATAC-seq
  • Experience of automation for NGS library construction
  • Supervisory Skills

Other information

The Wellcome Sanger Institute is a charitably funded research centre and committed to training the next generation of genome scientists. Focused on understanding the role of genetics in health and disease and a world leader in the genomic revolution, our mission is to use genome sequences to advance understanding of human and pathogen biology in order to improve human health. We aim to provide results that can be translated into diagnostics, treatments or therapies that reduce global health burdens. Our science is large-scale and organised into Programmes, led by our Faculty who conceive and deliver our science, and supported by our Scientific Operations teams responsible for all data production pipelines at the Institute. 

Our Campus: Set over 125 acres, the stunning and dynamic Wellcome Genome Campus is the biggest aggregate concentration of people in the world working on the common theme of Genomes and BioData. It brings together a diverse and exceptional scientific community, committed to delivering life-changing science with the reach, scale and imagination to pursue some of humanity’s greatest challenges.

Our Benefits: Our employees have access to a comprehensive range of benefits and facilities including:

  • Group Defined Contribution Pension Scheme and Life Assurance
  • Group Income Protection
  • Private Health Insurance
  • 25 days annual leave, increasing by one day a year to a maximum of 30
  • Family friendly environment including options for flexible and part-time working, a childcare voucher scheme, Campus Nursery and Summer holiday club
  • Two days paid Employee Volunteering Leave a year
  • Employee Discount Scheme
  • Campus Gym, tennis courts, cricket pitch and sports hall plus a range of dining facilities
  • Active Campus Sports and Social Club
  • Free Campus Bus Service

Genome Research Limited hold an Athena SWAN Bronze Award and will consider all individuals without discrimination and are committed to creating an inclusive environment for all employees, where everyone can thrive.

Please include a covering letter and CV with your application. Closing date for applications: 13th May 2019