Advanced Research Assistant

Open Targets

Salary range £26,960 - £32,622 depending on experience plus excellent benefits

Fixed term for 3 years.

A position is now available for a highly motivated Advanced Research Assistant to join the research group of Dr. Ana Cvejic, Dr Peter Campbell and Open Targets partners at the Wellcome Sanger Institute.

Open Targets aims to provide evidence on the biological validity of therapeutic targets and provide an initial assessment of the likely effectiveness of pharmacological intervention on these targets, using genome-scale experiments and analysis. This pioneering public-private partnership between Sanofi, Celgene, EMBL-EBI, GlaxoSmithKline, Takeda, and the Wellcome Sanger Institute, aims to provide a R&D framework that applies to all aspects of human disease, and to share its data openly with the scientific community (http://www.opentargets.org).

We are seeking an enthusiastic Advanced Research Assistant to carry out both routine and more bespoke laboratory protocols and procedures. The research focuses on the regulation of haematopoiesis in homeostasis and disease.  You will work as part of the team to provide laboratory support for the lab members. You will be working with a number of molecular biology techniques, in particular single cell transcriptomics, epigenetics and in vitro cell culture. You will be able to use your skills and experience to troubleshoot and innovate where required. Excellent verbal and email communication is essential to keep both the team and senior staff fully appraised of progress.

 

Job Reference
83467

Essential Skills

  • Degree in biological sciences or relevant subject.
  • Extensive laboratory experience .
  • An excellent understanding and proven practical experience in molecular biology strategies and techniques (e.g. qPCR, PCR, gel electrophoresis, nucleic acid isolation and purification).
  • Capable of working to a schedule and delivery of a variety of challenging projects simultaneously within agreed deadlines.
  • Ability to test and implement new approaches and techniques including troubleshooting.
  • Ability to work both as part of a team and also independently once appropriate training and guidance have been provided.
  • Excellent communication skills to allow accurate information to be exchanged (verbal, email, telephone).
  • Good computer skills in the use of office software (e.g. Excel, Word, Powerpoint).
  • Good understanding of relevant molecular biology techniques (PCR, CRISPR).

Ideal Skills

  • Theoretical understanding of flow cytometry. 
  • Understanding of genotyping techniques (e.g. qPCR). 
  • Experience in cell culture 
  • Good experience and understanding of software (Prism, FloJo) 

 

 

 

 

Other information

Open Targets is a pioneering public-private initiative between GlaxoSmithKline (GSK), Takeda, Celgene, Sanofi, EMBL-EBI (European Bioinformatics Institute) and the WSI (Wellcome Sanger Institute), located on the Wellcome Genome Campus in Hinxton, near Cambridge, UK.

Open Targets aims to generate evidence on the biological validity of therapeutic targets and provide an initial assessment of the likely effectiveness of pharmacological intervention on these targets, using genome-scale experiments and analysis. Open Targets aims to provide an R&D framework that applies to all aspects of human disease, to improve the success rate for discovering new medicines and share its data openly in the interests of accelerating drug discovery.

Our Campus: Set over 125 acres, the stunning and dynamic Wellcome Genome Campus is the biggest aggregate concentration of people in the world working on the common theme of Genomes and BioData. It brings together a diverse and exceptional scientific community, committed to delivering life-changing science with the reach, scale and imagination to pursue some of humanity’s greatest challenges.

Our Benefits: Our employees have access to a comprehensive range of benefits and facilities including:

  • Defined Contribution Pension Scheme and Life Assurance
  • Group Income Protection
  • Private Health Insurance
  • 25 days annual leave, increasing by one day a year to a maximum of 30
  • Family friendly environment including options for flexible and part-time working, a childcare voucher scheme and Campus Nursery
  • Two days paid Employee Volunteering Leave a year
  • Employee Discount Scheme
  • Campus Gym, tennis courts, cricket pitch and sports hall plus a range of dining facilities
  • Active Campus Sports and Social Club
  • Free Campus Bus Service

Genome Research Limited hold an Athena SWAN Bronze Award and will consider all individuals without discrimination and are committed to creating an inclusive environment for all employees, where everyone can thrive.

Please include a covering letter and CV with your application.

Closing date: 2nd June 2019